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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MC1R
All Species:
32.42
Human Site:
T157
Identified Species:
79.26
UniProt:
Q01726
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01726
NP_002377.4
317
34706
T157
L
R
Y
H
S
I
V
T
L
P
R
A
R
R
A
Chimpanzee
Pan troglodytes
Q9TUK4
317
34681
T157
L
R
Y
H
S
I
V
T
L
P
R
A
R
R
A
Rhesus Macaque
Macaca mulatta
Q864J4
317
34745
T157
L
R
Y
H
S
I
V
T
L
P
R
A
Q
R
A
Dog
Lupus familis
XP_541099
632
70219
T462
L
R
Y
H
H
I
M
T
V
R
R
S
R
V
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_032585
315
35208
T155
L
R
Y
H
S
I
V
T
L
P
R
A
R
R
A
Rat
Rattus norvegicus
NP_037231
332
36868
T162
L
Q
Y
H
N
I
M
T
V
R
R
V
G
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505445
334
36107
T164
L
Q
Y
H
T
I
M
T
G
R
R
V
G
T
I
Chicken
Gallus gallus
NP_001026633
314
35346
T155
L
R
Y
H
S
I
M
T
L
Q
R
A
V
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_851301
323
36614
T162
L
R
Y
H
S
I
M
T
T
Q
R
A
V
G
I
Tiger Blowfish
Takifugu rubipres
NP_001027732
322
35956
T158
L
R
Y
H
N
I
V
T
L
R
R
A
S
L
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
92.7
25.9
N.A.
76.3
46.6
N.A.
48.2
58.9
N.A.
53.8
50
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
94.6
36.5
N.A.
83.2
62.3
N.A.
60.7
73.8
N.A.
67.4
66.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
53.3
N.A.
100
40
N.A.
40
66.6
N.A.
60
66.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
100
66.6
N.A.
60
73.3
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
20
10
0
% G
% His:
0
0
0
100
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
100
0
0
0
0
0
0
0
10
40
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
100
0
0
0
0
0
0
0
60
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% P
% Gln:
0
20
0
0
0
0
0
0
0
20
0
0
10
0
0
% Q
% Arg:
0
80
0
0
0
0
0
0
0
40
100
0
40
40
0
% R
% Ser:
0
0
0
0
60
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
10
0
0
100
10
0
0
0
0
10
10
% T
% Val:
0
0
0
0
0
0
50
0
20
0
0
20
20
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _