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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC10
All Species:
35.45
Human Site:
Y419
Identified Species:
70.91
UniProt:
Q01780
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01780
NP_002676.1
885
100831
Y419
N
V
D
S
N
K
Q
Y
Q
L
A
D
W
R
I
Chimpanzee
Pan troglodytes
XP_514382
885
100746
Y419
N
V
D
S
N
K
Q
Y
Q
L
A
D
W
R
I
Rhesus Macaque
Macaca mulatta
XP_001103014
884
100980
Y419
N
V
D
S
N
K
Q
Y
Q
L
A
D
W
R
I
Dog
Lupus familis
XP_535408
1012
115406
Y545
S
V
E
S
N
K
Q
Y
Q
L
A
D
W
R
I
Cat
Felis silvestris
Mouse
Mus musculus
P56960
887
100953
Y419
G
V
E
S
N
K
Q
Y
Q
L
A
D
W
R
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012748
910
103885
Y437
S
V
D
A
D
K
Q
Y
Q
L
A
D
W
R
I
Frog
Xenopus laevis
NP_001084822
883
101879
Y415
N
V
E
S
D
K
R
Y
Q
L
A
D
W
R
I
Zebra Danio
Brachydanio rerio
NP_957383
899
102353
Y417
D
V
S
S
D
K
R
Y
Q
L
A
D
W
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097795
900
102900
L402
D
L
D
V
D
K
S
L
Q
L
A
D
W
R
M
Honey Bee
Apis mellifera
XP_396975
722
84430
D312
E
D
K
D
Y
L
I
D
T
L
S
L
R
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198503
819
91757
Y395
Q
V
E
A
D
K
Q
Y
Q
L
A
D
W
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12149
733
84020
R325
S
K
A
I
G
L
P
R
H
S
L
A
Y
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
77.9
N.A.
87
N.A.
N.A.
N.A.
70.8
65.1
59.8
N.A.
30.7
34.5
N.A.
38.7
Protein Similarity:
100
99.8
98.6
82.2
N.A.
92.2
N.A.
N.A.
N.A.
82.6
79.8
75.8
N.A.
51.1
53.4
N.A.
56.2
P-Site Identity:
100
100
100
86.6
N.A.
86.6
N.A.
N.A.
N.A.
80
80
73.3
N.A.
53.3
6.6
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
100
100
93.3
N.A.
80
13.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
0
0
0
0
0
84
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
42
9
42
0
0
9
0
0
0
84
0
0
0
% D
% Glu:
9
0
34
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
75
% I
% Lys:
0
9
9
0
0
84
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
17
0
9
0
92
9
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
34
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
59
0
84
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
9
0
0
0
0
9
84
0
% R
% Ser:
25
0
9
59
0
0
9
0
0
9
9
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
75
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
84
0
0
% W
% Tyr:
0
0
0
0
9
0
0
75
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _