KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFKP
All Species:
28.48
Human Site:
S142
Identified Species:
52.22
UniProt:
Q01813
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01813
NP_002618.1
784
85596
S142
N
L
F
R
K
E
W
S
G
L
L
E
E
L
A
Chimpanzee
Pan troglodytes
XP_507625
746
81795
S135
N
V
V
G
M
V
G
S
I
D
N
D
F
C
G
Rhesus Macaque
Macaca mulatta
XP_001118490
717
78539
I131
L
H
R
I
I
E
V
I
D
A
I
M
T
T
A
Dog
Lupus familis
XP_535201
901
98160
S253
N
I
F
R
K
E
W
S
G
L
L
E
E
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUA3
784
85437
S141
N
L
F
R
K
E
W
S
G
L
L
E
E
L
A
Rat
Rattus norvegicus
P47860
788
85702
S142
N
L
F
R
K
E
W
S
G
L
L
E
E
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511162
864
94802
S213
N
L
F
R
E
E
W
S
G
L
L
E
E
L
A
Chicken
Gallus gallus
NP_989554
769
83907
S142
T
A
E
E
A
K
K
S
S
H
L
N
I
V
G
Frog
Xenopus laevis
NP_001091319
786
86623
D138
E
E
W
S
G
L
L
D
E
L
V
Q
N
G
K
Zebra Danio
Brachydanio rerio
XP_002666643
787
86261
S135
N
L
F
R
E
E
W
S
G
L
L
A
E
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52034
788
86630
S135
N
L
F
R
Q
E
W
S
S
L
L
D
E
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27483
756
83282
E135
F
G
E
E
L
F
A
E
G
K
I
T
E
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16862
959
104599
P315
D
L
F
R
S
E
W
P
S
L
I
E
E
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
89.4
78.9
N.A.
88.5
87.9
N.A.
77.1
70.7
81.3
79.6
N.A.
58.8
N.A.
40.6
N.A.
Protein Similarity:
100
95
90.4
83.5
N.A.
93.6
93.4
N.A.
84.1
82
90.5
89.3
N.A.
75.8
N.A.
59.6
N.A.
P-Site Identity:
100
13.3
13.3
93.3
N.A.
100
100
N.A.
93.3
13.3
6.6
80
N.A.
73.3
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
20
100
N.A.
100
100
N.A.
100
26.6
26.6
86.6
N.A.
86.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
0
0
8
0
8
0
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
8
8
8
0
16
0
0
0
% D
% Glu:
8
8
16
16
16
70
0
8
8
0
0
47
70
8
0
% E
% Phe:
8
0
62
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
8
8
0
8
0
54
0
0
0
0
8
16
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
8
8
0
0
8
8
0
24
0
8
0
0
% I
% Lys:
0
0
0
0
31
8
8
0
0
8
0
0
0
0
8
% K
% Leu:
8
54
0
0
8
8
8
0
0
70
62
0
0
62
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
62
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
62
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
70
24
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% T
% Val:
0
8
8
0
0
8
8
0
0
0
8
0
0
8
24
% V
% Trp:
0
0
8
0
0
0
62
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _