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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PFKP All Species: 14.85
Human Site: S72 Identified Species: 27.22
UniProt: Q01813 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01813 NP_002618.1 784 85596 S72 Q G M V D G G S N I A E A D W
Chimpanzee Pan troglodytes XP_507625 746 81795 E67 C Q A F R T R E G R L K A A C
Rhesus Macaque Macaca mulatta XP_001118490 717 78539 S63 C V I G G D G S L T G A N L F
Dog Lupus familis XP_535201 901 98160 S183 Q G M V D G G S N I V E A D W
Cat Felis silvestris
Mouse Mus musculus Q9WUA3 784 85437 S71 Q G L V D G G S N I V E A K W
Rat Rattus norvegicus P47860 788 85702 S72 Q G M V D G G S N I V E A K W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511162 864 94802 D143 Q G M V D G G D N I V E V S W
Chicken Gallus gallus NP_989554 769 83907 V72 M L Q L G G T V I G S A R C Q
Frog Xenopus laevis NP_001091319 786 86623 S70 G D N I E E V S W E S V S S I
Zebra Danio Brachydanio rerio XP_002666643 787 86261 I67 M V D G G D N I K E A T W E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52034 788 86630 I67 M V D G G D C I Q E A N W A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27483 756 83282 A67 L A K W A H V A N V T H L G G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P16862 959 104599 E245 G L V R G G P E Y I K E F H W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 89.4 78.9 N.A. 88.5 87.9 N.A. 77.1 70.7 81.3 79.6 N.A. 58.8 N.A. 40.6 N.A.
Protein Similarity: 100 95 90.4 83.5 N.A. 93.6 93.4 N.A. 84.1 82 90.5 89.3 N.A. 75.8 N.A. 59.6 N.A.
P-Site Identity: 100 6.6 13.3 93.3 N.A. 80 86.6 N.A. 73.3 6.6 6.6 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 26.6 93.3 N.A. 86.6 86.6 N.A. 73.3 20 33.3 13.3 N.A. 6.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 0 0 8 0 0 24 16 39 16 0 % A
% Cys: 16 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % C
% Asp: 0 8 16 0 39 24 0 8 0 0 0 0 0 16 0 % D
% Glu: 0 0 0 0 8 8 0 16 0 24 0 47 0 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 8 % F
% Gly: 16 39 0 24 39 54 47 0 8 8 8 0 0 8 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 8 0 8 0 % H
% Ile: 0 0 8 8 0 0 0 16 8 47 0 0 0 0 8 % I
% Lys: 0 0 8 0 0 0 0 0 8 0 8 8 0 16 0 % K
% Leu: 8 16 8 8 0 0 0 0 8 0 8 0 8 8 0 % L
% Met: 24 0 31 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 47 0 0 8 8 0 8 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 39 8 8 0 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 8 0 8 0 0 8 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 47 0 0 16 0 8 16 8 % S
% Thr: 0 0 0 0 0 8 8 0 0 8 8 8 0 0 0 % T
% Val: 0 24 8 39 0 0 16 8 0 8 31 8 8 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 8 0 0 0 16 0 47 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _