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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PFKP All Species: 4.55
Human Site: T712 Identified Species: 8.33
UniProt: Q01813 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01813 NP_002618.1 784 85596 T712 R G R G K K F T T D D S I C V
Chimpanzee Pan troglodytes XP_507625 746 81795 T674 R G R G K K F T T D D S V C V
Rhesus Macaque Macaca mulatta XP_001118490 717 78539 K657 V C V L G I S K R N V I F Q P
Dog Lupus familis XP_535201 901 98160 V823 P G K G K R F V T D D S I C V
Cat Felis silvestris
Mouse Mus musculus Q9WUA3 784 85437 V711 Q G T G K K F V S D D S I C V
Rat Rattus norvegicus P47860 788 85702 V712 H G T G K K F V S D D S I C V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511162 864 94802 A783 Y R K G K I F A N T D D S V C
Chicken Gallus gallus NP_989554 769 83907 A690 S R H G R I F A N T A D S A C
Frog Xenopus laevis NP_001091319 786 86623 V704 Y R K D E G R V F A N T D D S
Zebra Danio Brachydanio rerio XP_002666643 787 86261 A705 Y R R G R V F A N T E D S A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52034 788 86630 N711 I D A N G V V N C K S P D T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27483 756 83282 K695 E G I V N P V K M G D R D C C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P16862 959 104599 E894 A E A R A A E E N F N A D D K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 89.4 78.9 N.A. 88.5 87.9 N.A. 77.1 70.7 81.3 79.6 N.A. 58.8 N.A. 40.6 N.A.
Protein Similarity: 100 95 90.4 83.5 N.A. 93.6 93.4 N.A. 84.1 82 90.5 89.3 N.A. 75.8 N.A. 59.6 N.A.
P-Site Identity: 100 93.3 0 73.3 N.A. 73.3 73.3 N.A. 26.6 13.3 0 20 N.A. 0 N.A. 20 N.A.
P-Site Similarity: 100 100 6.6 86.6 N.A. 86.6 80 N.A. 33.3 20 26.6 33.3 N.A. 0 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 8 8 0 24 0 8 8 8 0 16 8 % A
% Cys: 0 8 0 0 0 0 0 0 8 0 0 0 0 47 31 % C
% Asp: 0 8 0 8 0 0 0 0 0 39 54 24 31 16 0 % D
% Glu: 8 8 0 0 8 0 8 8 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 62 0 8 8 0 0 8 0 0 % F
% Gly: 0 47 0 62 16 8 0 0 0 8 0 0 0 0 0 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 24 0 0 0 0 0 8 31 0 0 % I
% Lys: 0 0 24 0 47 31 0 16 0 8 0 0 0 0 8 % K
% Leu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 8 31 8 16 0 0 0 0 % N
% Pro: 8 0 0 0 0 8 0 0 0 0 0 8 0 0 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 16 31 24 8 16 8 8 0 8 0 0 8 0 0 0 % R
% Ser: 8 0 0 0 0 0 8 0 16 0 8 39 24 0 8 % S
% Thr: 0 0 16 0 0 0 0 16 24 24 0 8 0 8 0 % T
% Val: 8 0 8 8 0 16 16 31 0 0 8 0 8 8 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _