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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFKP
All Species:
40.61
Human Site:
Y654
Identified Species:
74.44
UniProt:
Q01813
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01813
NP_002618.1
784
85596
Y654
T
D
F
I
Y
Q
L
Y
S
E
E
G
K
G
V
Chimpanzee
Pan troglodytes
XP_507625
746
81795
Y616
T
D
F
I
Y
Q
L
Y
S
E
E
G
K
G
V
Rhesus Macaque
Macaca mulatta
XP_001118490
717
78539
G608
V
L
G
H
M
Q
Q
G
G
A
P
S
P
F
D
Dog
Lupus familis
XP_535201
901
98160
Y765
T
D
F
I
Y
Q
L
Y
S
E
E
G
K
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUA3
784
85437
Y653
T
D
F
I
Y
Q
L
Y
S
E
E
G
K
G
V
Rat
Rattus norvegicus
P47860
788
85702
Y654
T
D
F
I
Y
Q
L
Y
S
E
E
G
K
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511162
864
94802
Y725
T
D
F
I
Y
Q
L
Y
S
E
E
G
K
G
V
Chicken
Gallus gallus
NP_989554
769
83907
Y632
T
D
F
I
Y
N
L
Y
T
E
E
G
K
G
I
Frog
Xenopus laevis
NP_001091319
786
86623
Y646
T
D
F
I
Y
Q
L
Y
S
E
E
G
R
G
V
Zebra Danio
Brachydanio rerio
XP_002666643
787
86261
Y647
T
D
F
I
Y
Q
L
Y
T
E
E
G
K
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52034
788
86630
Y653
T
D
F
I
Y
R
L
Y
S
E
E
G
K
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27483
756
83282
I646
Y
S
P
D
V
K
K
I
F
D
K
V
M
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16862
959
104599
L832
K
A
L
S
A
T
K
L
A
E
V
I
T
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
89.4
78.9
N.A.
88.5
87.9
N.A.
77.1
70.7
81.3
79.6
N.A.
58.8
N.A.
40.6
N.A.
Protein Similarity:
100
95
90.4
83.5
N.A.
93.6
93.4
N.A.
84.1
82
90.5
89.3
N.A.
75.8
N.A.
59.6
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
80
93.3
93.3
N.A.
86.6
N.A.
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
100
93.3
100
100
N.A.
100
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
77
0
8
0
0
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
85
77
0
0
0
8
% E
% Phe:
0
0
77
0
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
8
8
0
0
77
0
77
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
77
0
0
0
8
0
0
0
8
0
0
8
% I
% Lys:
8
0
0
0
0
8
16
0
0
0
8
0
70
8
0
% K
% Leu:
0
8
8
0
0
0
77
8
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
0
0
0
0
0
70
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
8
0
0
0
0
62
0
0
8
0
0
0
% S
% Thr:
77
0
0
0
0
8
0
0
16
0
0
0
8
0
0
% T
% Val:
8
0
0
0
8
0
0
0
0
0
8
8
0
0
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
77
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _