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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPC
All Species:
17.58
Human Site:
S291
Identified Species:
38.67
UniProt:
Q01831
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01831
NP_001139241.1
940
105981
S291
E
R
R
F
A
I
Y
S
A
R
D
D
E
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092063
940
106039
S291
E
R
R
F
A
I
Y
S
A
R
D
D
E
E
L
Dog
Lupus familis
XP_533727
1000
111293
S348
E
R
R
F
A
I
Y
S
A
R
D
D
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P51612
930
104503
S287
E
R
R
I
A
I
Y
S
A
R
D
N
E
E
L
Rat
Rattus norvegicus
NP_001101344
933
104842
S288
E
R
R
I
A
I
Y
S
A
R
D
N
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507457
701
80875
K148
D
C
M
P
Y
E
K
K
G
S
S
S
S
F
E
Chicken
Gallus gallus
XP_414379
933
106345
A297
E
R
R
F
A
I
Y
A
A
R
D
D
E
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038675
879
100439
L278
E
M
T
Y
L
F
L
L
V
L
R
S
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24595
1293
144205
K385
D
R
Q
I
L
L
H
K
V
S
L
M
C
Q
I
Honey Bee
Apis mellifera
XP_624876
506
58802
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786323
1660
184963
I422
K
S
T
L
F
D
E
I
E
K
K
E
D
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.6
73.8
N.A.
74
74.3
N.A.
38.2
59.8
N.A.
47.5
N.A.
20
25.8
N.A.
26.6
Protein Similarity:
100
N.A.
97.7
81.8
N.A.
82.7
82.8
N.A.
49.3
71.4
N.A.
63.6
N.A.
35.5
38.1
N.A.
39.2
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
0
93.3
N.A.
13.3
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
6.6
100
N.A.
20
N.A.
46.6
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
55
0
0
10
55
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
19
0
0
0
0
10
0
0
0
0
55
37
10
10
0
% D
% Glu:
64
0
0
0
0
10
10
0
10
0
0
10
55
55
10
% E
% Phe:
0
0
0
37
10
10
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
28
0
55
0
10
0
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
0
0
10
19
0
10
10
0
0
0
10
% K
% Leu:
0
0
0
10
19
10
10
10
0
10
10
0
10
0
64
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
64
55
0
0
0
0
0
0
55
10
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
0
46
0
19
10
19
10
0
0
% S
% Thr:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
55
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _