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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPC All Species: 26.06
Human Site: Y704 Identified Species: 57.33
UniProt: Q01831 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01831 NP_001139241.1 940 105981 Y704 V R L G E V P Y K M V K G F S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092063 940 106039 Y704 V R L G E V P Y K M V K G F S
Dog Lupus familis XP_533727 1000 111293 Y765 V R L G E V P Y K M V K G Y S
Cat Felis silvestris
Mouse Mus musculus P51612 930 104503 Y697 V R L G E V P Y K M V K G F S
Rat Rattus norvegicus NP_001101344 933 104842 Y698 V R L G E V P Y K M V K G F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507457 701 80875 V526 C S E D D K W V S L D C V H G
Chicken Gallus gallus XP_414379 933 106345 Y701 V R I G E V P Y K M V K G Y S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038675 879 100439 K663 M S E Q K N V K D L A L F G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24595 1293 144205 L895 D G G D D V P L P K K R P K L
Honey Bee Apis mellifera XP_624876 506 58802 R331 P Y K I V T A R P K Y D K L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786323 1660 184963 Y1434 I R I G E K P Y K M V K P R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.6 73.8 N.A. 74 74.3 N.A. 38.2 59.8 N.A. 47.5 N.A. 20 25.8 N.A. 26.6
Protein Similarity: 100 N.A. 97.7 81.8 N.A. 82.7 82.8 N.A. 49.3 71.4 N.A. 63.6 N.A. 35.5 38.1 N.A. 39.2
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 0 86.6 N.A. 0 N.A. 13.3 6.6 N.A. 60
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 13.3 100 N.A. 26.6 N.A. 26.6 6.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 19 19 0 0 0 10 0 10 10 0 0 0 % D
% Glu: 0 0 19 0 64 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 37 0 % F
% Gly: 0 10 10 64 0 0 0 0 0 0 0 0 55 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 10 0 19 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 10 19 0 10 64 19 10 64 10 10 0 % K
% Leu: 0 0 46 0 0 0 0 10 0 19 0 10 0 10 10 % L
% Met: 10 0 0 0 0 0 0 0 0 64 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 73 0 19 0 0 0 19 0 10 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 64 0 0 0 0 0 10 0 0 0 10 0 10 0 % R
% Ser: 0 19 0 0 0 0 0 0 10 0 0 0 0 0 64 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % T
% Val: 55 0 0 0 10 64 10 10 0 0 64 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 64 0 0 10 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _