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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EWSR1
All Species:
26.67
Human Site:
S224
Identified Species:
83.81
UniProt:
Q01844
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01844
NP_005234.1
656
68478
S224
P
S
S
Y
G
Q
Q
S
S
Y
G
Q
Q
S
S
Chimpanzee
Pan troglodytes
XP_001173222
656
68478
S224
P
S
S
Y
G
Q
Q
S
S
Y
G
Q
Q
S
S
Rhesus Macaque
Macaca mulatta
XP_001104800
656
68505
S224
P
S
S
Y
G
Q
Q
S
S
Y
G
Q
Q
S
S
Dog
Lupus familis
XP_865186
656
68415
S224
P
S
S
Y
G
Q
Q
S
S
Y
G
Q
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61545
655
68400
S224
P
S
S
Y
G
Q
Q
S
S
Y
G
Q
Q
S
S
Rat
Rattus norvegicus
NP_001020803
655
68313
S224
P
S
S
Y
G
Q
Q
S
S
Y
G
Q
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516464
779
81315
S348
Q
S
S
Y
G
Q
P
S
S
Y
G
Q
Q
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27294
399
38820
K147
F
G
A
I
G
I
I
K
K
D
K
R
T
M
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
99.2
N.A.
98
98.4
N.A.
80
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
N.A.
N.A.
Protein Similarity:
100
100
100
99.5
N.A.
99.2
99.5
N.A.
82.5
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
100
0
0
0
0
0
88
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
13
13
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
13
13
0
13
0
0
0
13
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
75
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
88
75
0
0
0
0
88
88
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
0
88
88
0
0
0
0
88
88
0
0
0
0
88
88
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
88
0
0
0
0
0
88
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _