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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDR2 All Species: 22.42
Human Site: S139 Identified Species: 44.85
UniProt: Q01850 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01850 NP_001793.1 454 51855 S139 Q V E E L K S S G Q G R R S P
Chimpanzee Pan troglodytes XP_523717 465 52923 L139 Q V E Q L R G L E Q L R V L R
Rhesus Macaque Macaca mulatta XP_001092798 454 51959 S139 Q V E E L K S S G R G R R S Q
Dog Lupus familis XP_536938 447 51170 S135 Q V E E L K S S G Q R R R S Q
Cat Felis silvestris
Mouse Mus musculus P97817 455 52082 S138 Q V E E L K S S S Q G R G R Q
Rat Rattus norvegicus NP_001020853 453 52016 S137 S Q V E E L K S N Q G R G R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508235 459 52412 S139 Q V E E L K T S S R S K G S Q
Chicken Gallus gallus Q5ZJA3 456 52829 S139 Q V E E L K K S G R G R M N H
Frog Xenopus laevis Q6GLX3 493 57460 N175 L K S L R E E N R D L T I S R
Zebra Danio Brachydanio rerio Q6NZT2 464 53019 L139 R V E E L R T L E E L R V R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8SWR2 620 70217 S254 S L Q E H V N S L E S I K T E
Honey Bee Apis mellifera XP_392258 755 85147 Q159 K I D E I N E Q H E S L L R Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.9 98.2 87.6 N.A. 88.7 87.8 N.A. 74.7 71 21.1 44.1 N.A. 21.7 22.7 N.A. N.A.
Protein Similarity: 100 62.1 99.1 90.9 N.A. 92.7 93.1 N.A. 86.2 83.1 41.3 61.4 N.A. 38 37.4 N.A. N.A.
P-Site Identity: 100 40 86.6 86.6 N.A. 73.3 33.3 N.A. 53.3 66.6 6.6 33.3 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 53.3 93.3 86.6 N.A. 73.3 33.3 N.A. 73.3 80 20 60 N.A. 53.3 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 67 84 9 9 17 0 17 25 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 34 0 42 0 25 0 0 % G
% His: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 9 % H
% Ile: 0 9 0 0 9 0 0 0 0 0 0 9 9 0 0 % I
% Lys: 9 9 0 0 0 50 17 0 0 0 0 9 9 0 0 % K
% Leu: 9 9 0 9 67 9 0 17 9 0 25 9 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 9 9 9 9 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 59 9 9 9 0 0 0 9 0 42 0 0 0 0 50 % Q
% Arg: 9 0 0 0 9 17 0 0 9 25 9 67 25 34 25 % R
% Ser: 17 0 9 0 0 0 34 67 17 0 25 0 0 42 0 % S
% Thr: 0 0 0 0 0 0 17 0 0 0 0 9 0 9 0 % T
% Val: 0 67 9 0 0 9 0 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _