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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDR2
All Species:
25.15
Human Site:
Y173
Identified Species:
50.3
UniProt:
Q01850
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01850
NP_001793.1
454
51855
Y173
D
L
R
Q
H
F
V
Y
D
H
V
F
A
E
K
Chimpanzee
Pan troglodytes
XP_523717
465
52923
A173
T
S
P
R
C
K
D
A
F
R
L
H
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001092798
454
51959
Y173
D
L
R
Q
H
F
V
Y
D
H
V
F
A
E
K
Dog
Lupus familis
XP_536938
447
51170
Y169
D
L
R
Q
H
F
V
Y
D
H
V
F
A
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P97817
455
52082
Y172
D
L
R
Q
H
F
V
Y
D
H
V
F
A
E
K
Rat
Rattus norvegicus
NP_001020853
453
52016
Y171
D
L
R
Q
H
F
V
Y
D
H
V
F
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508235
459
52412
H173
D
L
R
K
H
F
V
H
D
H
V
F
A
E
K
Chicken
Gallus gallus
Q5ZJA3
456
52829
Y173
D
L
R
Q
Y
F
V
Y
D
H
V
F
A
E
K
Frog
Xenopus laevis
Q6GLX3
493
57460
Q209
N
K
K
E
M
E
S
Q
T
K
Q
L
Q
D
E
Zebra Danio
Brachydanio rerio
Q6NZT2
464
53019
S173
T
A
P
R
Y
E
D
S
F
M
V
S
D
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SWR2
620
70217
S288
E
E
K
E
S
L
T
S
S
L
E
E
S
S
D
Honey Bee
Apis mellifera
XP_392258
755
85147
S193
V
S
V
T
Q
G
S
S
T
Q
Q
N
A
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.9
98.2
87.6
N.A.
88.7
87.8
N.A.
74.7
71
21.1
44.1
N.A.
21.7
22.7
N.A.
N.A.
Protein Similarity:
100
62.1
99.1
90.9
N.A.
92.7
93.1
N.A.
86.2
83.1
41.3
61.4
N.A.
38
37.4
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
86.6
93.3
0
6.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
33.3
20
N.A.
26.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
0
0
0
67
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
0
0
0
0
0
17
0
59
0
0
0
9
9
9
% D
% Glu:
9
9
0
17
0
17
0
0
0
0
9
9
0
59
9
% E
% Phe:
0
0
0
0
0
59
0
0
17
0
0
59
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
50
0
0
9
0
59
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
17
9
0
9
0
0
0
9
0
0
0
0
59
% K
% Leu:
0
59
0
0
0
9
0
0
0
9
9
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
0
0
0
50
9
0
0
9
0
9
17
0
9
0
0
% Q
% Arg:
0
0
59
17
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
17
0
0
9
0
17
25
9
0
0
9
17
17
9
% S
% Thr:
17
0
0
9
0
0
9
0
17
0
0
0
0
0
0
% T
% Val:
9
0
9
0
0
0
59
0
0
0
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _