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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU4F1 All Species: 43.64
Human Site: S362 Identified Species: 80
UniProt: Q01851 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01851 NP_006228.3 420 42754 S362 E K K R K R T S I A A P E K R
Chimpanzee Pan troglodytes XP_526699 406 42885 S348 E K K R K R T S I A A P E K R
Rhesus Macaque Macaca mulatta Q28503 291 32940 L253 R M A E E L N L E K E V V R V
Dog Lupus familis XP_544328 338 36988 S280 E R K R K R T S I A A P E K R
Cat Felis silvestris
Mouse Mus musculus P17208 421 42763 S363 E K K R K R T S I A A P E K R
Rat Rattus norvegicus P20266 128 14214 K90 T S I A A P E K R S L E A Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q91998 341 37755 S283 D K K R K R T S I A A P E K R
Frog Xenopus laevis P70030 385 41967 S302 R K R K K R T S I E V S V K G
Zebra Danio Brachydanio rerio Q90435 331 36531 S273 E R K R K R T S I A A P E K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24350 396 43685 S326 E K K R K R T S I A A P E K R
Honey Bee Apis mellifera XP_394134 364 38864 S306 E K K R K R T S I A A P E K R
Nematode Worm Caenorhab. elegans P13528 467 52296 S369 D K K R K R T S I A A P E K R
Sea Urchin Strong. purpuratus XP_786727 349 37858 S290 D K K R K R T S I A A P E K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.4 29.7 59.5 N.A. 99 30.4 N.A. N.A. 60.9 29.2 57.1 N.A. 47.6 50.4 30.8 48.8
Protein Similarity: 100 54.5 42.8 66.4 N.A. 99 30.4 N.A. N.A. 67.1 43 63.5 N.A. 54.7 58.8 41.7 56.9
P-Site Identity: 100 100 0 93.3 N.A. 100 0 N.A. N.A. 93.3 46.6 93.3 N.A. 100 100 93.3 93.3
P-Site Similarity: 100 100 13.3 100 N.A. 100 6.6 N.A. N.A. 100 60 100 N.A. 100 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 0 0 0 0 77 77 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 54 0 0 8 8 0 8 0 8 8 8 8 77 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 85 0 0 0 0 0 0 % I
% Lys: 0 70 77 8 85 0 0 8 0 8 0 0 0 85 0 % K
% Leu: 0 0 0 0 0 8 0 8 0 0 8 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 77 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 16 8 77 0 85 0 0 8 0 0 0 0 8 77 % R
% Ser: 0 8 0 0 0 0 0 85 0 8 0 8 0 0 0 % S
% Thr: 8 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 8 16 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _