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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU4F1
All Species:
8.18
Human Site:
Y22
Identified Species:
15
UniProt:
Q01851
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01851
NP_006228.3
420
42754
Y22
P
T
L
P
E
H
K
Y
P
S
L
H
S
S
S
Chimpanzee
Pan troglodytes
XP_526699
406
42885
A38
S
T
S
P
G
S
S
A
P
T
A
P
S
A
S
Rhesus Macaque
Macaca mulatta
Q28503
291
32940
L23
N
S
D
A
S
A
T
L
P
L
I
M
H
H
S
Dog
Lupus familis
XP_544328
338
36988
S22
V
L
Q
E
P
K
F
S
S
L
H
S
G
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P17208
421
42763
Y22
P
T
L
P
E
H
K
Y
P
S
L
H
S
S
S
Rat
Rattus norvegicus
P20266
128
14214
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91998
341
37755
P22
I
L
H
E
P
K
Y
P
H
L
H
T
S
S
E
Frog
Xenopus laevis
P70030
385
41967
D22
G
S
S
I
V
H
A
D
P
G
G
M
Q
Q
A
Zebra Danio
Brachydanio rerio
Q90435
331
36531
G22
A
L
H
P
S
S
E
G
M
R
R
V
C
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24350
396
43685
Y24
P
S
C
F
P
G
R
Y
S
P
S
Y
R
S
S
Honey Bee
Apis mellifera
XP_394134
364
38864
A30
Y
S
P
P
P
Y
R
A
A
P
D
P
M
P
P
Nematode Worm
Caenorhab. elegans
P13528
467
52296
S22
F
P
V
P
L
L
V
S
V
L
I
F
H
H
S
Sea Urchin
Strong. purpuratus
XP_786727
349
37858
P23
P
G
G
P
K
Y
S
P
L
H
R
H
H
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
29.7
59.5
N.A.
99
30.4
N.A.
N.A.
60.9
29.2
57.1
N.A.
47.6
50.4
30.8
48.8
Protein Similarity:
100
54.5
42.8
66.4
N.A.
99
30.4
N.A.
N.A.
67.1
43
63.5
N.A.
54.7
58.8
41.7
56.9
P-Site Identity:
100
33.3
13.3
6.6
N.A.
100
0
N.A.
N.A.
13.3
13.3
6.6
N.A.
26.6
6.6
13.3
20
P-Site Similarity:
100
46.6
26.6
6.6
N.A.
100
0
N.A.
N.A.
13.3
26.6
13.3
N.A.
46.6
26.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
16
8
0
8
0
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
0
0
8
0
0
8
0
% D
% Glu:
0
0
0
16
16
0
8
0
0
0
0
0
0
0
16
% E
% Phe:
8
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
8
8
8
0
8
8
0
8
0
8
8
0
8
0
0
% G
% His:
0
0
16
0
0
24
0
0
8
8
16
24
24
16
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% I
% Lys:
0
0
0
0
8
16
16
0
0
0
0
0
0
0
0
% K
% Leu:
0
24
16
0
8
8
0
8
8
31
16
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
16
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
31
8
8
54
31
0
0
16
39
16
0
16
0
8
16
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
8
16
0
8
0
8
% R
% Ser:
8
31
16
0
16
16
16
16
16
16
8
8
31
39
47
% S
% Thr:
0
24
0
0
0
0
8
0
0
8
0
8
0
0
0
% T
% Val:
8
0
8
0
8
0
8
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
16
8
24
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _