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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU5F1 All Species: 15.76
Human Site: S37 Identified Species: 34.67
UniProt: Q01860 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01860 NP_002692.2 360 38571 S37 V D P R T W L S F Q G P P G G
Chimpanzee Pan troglodytes Q7YR49 360 38582 S37 V D P R T W L S F Q G P P G G
Rhesus Macaque Macaca mulatta Q5TM49 360 38511 S37 V D P R T W L S F Q G P P G G
Dog Lupus familis XP_538830 360 38329 S37 G D P R A W L S F P G P P G G
Cat Felis silvestris
Mouse Mus musculus P20263 352 38198 T33 P G W V D P R T W L S F Q G P
Rat Rattus norvegicus P56225 335 36982 S35 V D T P T W L S S Q A A T S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P15143 739 75964 N75 L N V Q S K S N E E S G D S Q
Frog Xenopus laevis P70030 385 41967 Q40 R D A Q T L V Q S D Y T L Q S
Zebra Danio Brachydanio rerio Q90270 472 51486 F51 L Q D P S L I F N K A H F N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 N65 L P S S P S P N G Q G N G G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20268 380 42556 N47 H L H H H L I N E N E M E A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.3 90.8 N.A. 84.1 50.2 N.A. N.A. 23 38.1 34.3 N.A. 33.4 N.A. 35.2 N.A.
Protein Similarity: 100 99.7 98.6 94.4 N.A. 89.1 60.8 N.A. N.A. 32 50.1 44.7 N.A. 44.5 N.A. 47.6 N.A.
P-Site Identity: 100 100 100 80 N.A. 6.6 46.6 N.A. N.A. 0 13.3 6.6 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 100 100 80 N.A. 20 46.6 N.A. N.A. 40 26.6 33.3 N.A. 40 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 0 0 0 19 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 55 10 0 10 0 0 0 0 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 19 10 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 37 0 0 10 10 0 0 % F
% Gly: 10 10 0 0 0 0 0 0 10 0 46 10 10 55 55 % G
% His: 10 0 10 10 10 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % K
% Leu: 28 10 0 0 0 28 46 0 0 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 28 10 10 0 10 0 10 0 % N
% Pro: 10 10 37 19 10 10 10 0 0 10 0 37 37 0 10 % P
% Gln: 0 10 0 19 0 0 0 10 0 46 0 0 10 10 10 % Q
% Arg: 10 0 0 37 0 0 10 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 10 10 19 10 10 46 19 0 19 0 0 19 10 % S
% Thr: 0 0 10 0 46 0 0 10 0 0 0 10 10 0 0 % T
% Val: 37 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 46 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _