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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPIB All Species: 6.06
Human Site: Y58 Identified Species: 22.22
UniProt: Q01892 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01892 NP_003112.2 262 28819 Y58 P P V P A T P Y E A F D P A A
Chimpanzee Pan troglodytes XP_524483 256 28193 Y52 P P V P A T P Y E A F D P A A
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O35906 267 29347 D63 I A P Y E A F D P A T A A F S
Rat Rattus norvegicus Q5EBA3 269 29381 P65 A A Y E A F D P A A T A A F A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990354 256 29683 Y52 H G D H Y W E Y H P H H V H S
Frog Xenopus laevis NP_001091252 273 31552 Y62 E D P C Y E T Y E N I H L T S
Zebra Danio Brachydanio rerio NP_932328 290 33927 F81 H H I H P V D F E N L P E S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 N.A. N.A. N.A. 83.5 83.2 N.A. N.A. 40.8 48.3 36.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95 N.A. N.A. N.A. 86.1 86.6 N.A. N.A. 54.5 63.3 50.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. N.A. N.A. 6.6 20 N.A. N.A. 6.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. N.A. N.A. 13.3 20 N.A. N.A. 13.3 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 29 0 0 43 15 0 0 15 58 0 29 29 29 43 % A
% Cys: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 15 0 0 0 29 15 0 0 0 29 0 0 0 % D
% Glu: 15 0 0 15 15 15 15 0 58 0 0 0 15 0 0 % E
% Phe: 0 0 0 0 0 15 15 15 0 0 29 0 0 29 0 % F
% Gly: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 29 15 0 29 0 0 0 0 15 0 15 29 0 15 15 % H
% Ile: 15 0 15 0 0 0 0 0 0 0 15 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 15 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % N
% Pro: 29 29 29 29 15 0 29 15 15 15 0 15 29 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 43 % S
% Thr: 0 0 0 0 0 29 15 0 0 0 29 0 0 15 0 % T
% Val: 0 0 29 0 0 15 0 0 0 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 15 29 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _