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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OCRL All Species: 1.82
Human Site: S854 Identified Species: 4
UniProt: Q01968 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01968 NP_000267.2 901 104205 S854 L K F S E Y N S V N A N M I A
Chimpanzee Pan troglodytes XP_513330 1149 128671 S1101 L R E L L K N S A K N H L D E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852376 902 104417 N856 L K F S K Y N N V S E N M I A
Cat Felis silvestris
Mouse Mus musculus Q9D2G5 1434 158462 A1287 P P R R K K S A P A A F H L Q
Rat Rattus norvegicus O55207 1496 165245 A1410 P R V T E P E A A S F H G D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517168 864 99967 N817 L K Y S E D N N V S T N M I A
Chicken Gallus gallus XP_420138 911 104497 N864 L K Y S E D N N V S A T M I A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2I6J1 1266 140353 E1155 V E Y P S G R E R G A S Q G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569962 850 97512 A804 L R S T E R A A W M D Y H S R
Honey Bee Apis mellifera XP_396184 846 96645 R801 I F G S I F L R D P P R S R G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797066 1060 119256 R1003 L M H S D D N R L D A K T L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.1 N.A. 95.1 N.A. 21.9 21.3 N.A. 81.2 76 N.A. 21.3 N.A. 27.8 40 N.A. 37.7
Protein Similarity: 100 55 N.A. 97.2 N.A. 36.1 35.7 N.A. 88.7 85.7 N.A. 36.9 N.A. 44.7 57.4 N.A. 53.8
P-Site Identity: 100 20 N.A. 73.3 N.A. 6.6 6.6 N.A. 66.6 66.6 N.A. 6.6 N.A. 13.3 6.6 N.A. 33.3
P-Site Similarity: 100 40 N.A. 93.3 N.A. 33.3 40 N.A. 86.6 86.6 N.A. 33.3 N.A. 33.3 20 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 28 19 10 46 0 0 0 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 28 0 0 10 10 10 0 0 19 0 % D
% Glu: 0 10 10 0 46 0 10 10 0 0 10 0 0 0 10 % E
% Phe: 0 10 19 0 0 10 0 0 0 0 10 10 0 0 0 % F
% Gly: 0 0 10 0 0 10 0 0 0 10 0 0 10 10 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 19 19 0 0 % H
% Ile: 10 0 0 0 10 0 0 0 0 0 0 0 0 37 0 % I
% Lys: 0 37 0 0 19 19 0 0 0 10 0 10 0 0 0 % K
% Leu: 64 0 0 10 10 0 10 0 10 0 0 0 10 19 0 % L
% Met: 0 10 0 0 0 0 0 0 0 10 0 0 37 0 0 % M
% Asn: 0 0 0 0 0 0 55 28 0 10 10 28 0 0 0 % N
% Pro: 19 10 0 10 0 10 0 0 10 10 10 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % Q
% Arg: 0 28 10 10 0 10 10 19 10 0 0 10 0 10 10 % R
% Ser: 0 0 10 55 10 0 10 19 0 37 0 10 10 10 0 % S
% Thr: 0 0 0 19 0 0 0 0 0 0 10 10 10 0 0 % T
% Val: 10 0 10 0 0 0 0 0 37 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 28 0 0 19 0 0 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _