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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB3
All Species:
19.39
Human Site:
S1227
Identified Species:
42.67
UniProt:
Q01970
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01970
NP_000923.1
1234
138799
S1227
L
S
G
A
D
S
E
S
Q
E
E
N
T
Q
L
Chimpanzee
Pan troglodytes
XP_001170216
1271
144286
K1251
D
P
G
K
V
N
H
K
T
P
S
S
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001115104
1234
138637
S1227
L
S
G
A
D
S
E
S
Q
E
E
N
T
Q
L
Dog
Lupus familis
XP_853283
1230
138739
S1223
L
S
G
A
D
S
E
S
Q
E
E
N
T
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P51432
1234
139473
S1227
L
S
S
A
D
S
E
S
Q
E
E
N
T
Q
L
Rat
Rattus norvegicus
Q99JE6
1234
139431
S1227
Q
S
G
A
D
S
E
S
Q
E
E
N
T
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
N1208
E
E
G
L
E
E
D
N
P
E
K
V
F
D
T
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
S1222
S
N
I
A
N
V
S
S
L
L
L
D
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
N1308
I
S
P
A
K
S
H
N
S
I
A
A
A
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
96.3
93.1
N.A.
91.9
92
N.A.
53.2
23.1
22.7
58.4
N.A.
40.3
N.A.
N.A.
N.A.
Protein Similarity:
100
70
97.1
96.1
N.A.
94.8
94.7
N.A.
71.5
32.6
35.4
74.3
N.A.
56.8
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
13.3
0
0
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
93.3
N.A.
40
0
0
40
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
64
0
0
0
0
0
0
10
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
46
0
10
0
0
0
0
10
0
10
0
% D
% Glu:
10
10
0
0
10
10
46
0
0
55
46
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
10
0
0
10
0
0
10
0
% K
% Leu:
37
0
0
10
0
0
0
0
10
10
10
0
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
10
0
19
0
0
0
46
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
46
0
0
0
0
37
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
55
10
0
0
55
10
55
10
0
10
10
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
46
0
19
% T
% Val:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _