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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL5
All Species:
8.79
Human Site:
S162
Identified Species:
17.58
UniProt:
Q02045
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02045
NP_002468.1
173
19534
S162
N
L
D
Y
K
A
L
S
Y
V
I
T
H
G
E
Chimpanzee
Pan troglodytes
XP_527844
193
21795
C183
N
L
D
Y
R
N
L
C
Y
I
I
T
H
G
E
Rhesus Macaque
Macaca mulatta
XP_001086310
190
20940
L162
G
A
P
G
V
S
W
L
E
A
H
A
E
P
E
Dog
Lupus familis
XP_536281
186
20662
S175
N
L
D
Y
K
A
L
S
Y
V
L
T
H
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QVP4
175
19431
C164
N
I
D
Y
K
S
L
C
Y
I
I
T
H
G
D
Rat
Rattus norvegicus
P08733
166
18862
V156
N
L
D
Y
K
N
L
V
H
I
I
T
H
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514366
206
23162
S195
N
L
D
Y
K
A
L
S
Y
T
I
T
H
G
E
Chicken
Gallus gallus
P02611
165
18771
C155
N
L
D
Y
K
N
L
C
Y
V
I
T
H
G
E
Frog
Xenopus laevis
NP_001087308
167
19067
V156
N
L
N
Y
K
N
L
V
H
I
I
T
H
G
E
Zebra Danio
Brachydanio rerio
NP_571404
172
19002
C160
N
I
D
Y
K
S
L
C
Y
I
I
T
H
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40423
174
19936
R162
F
D
Y
L
E
F
T
R
I
L
K
H
G
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09510
172
19922
R160
F
D
Y
V
E
F
T
R
M
L
K
H
G
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59
75.2
87
N.A.
63.4
62.4
N.A.
76.6
65.3
66.4
68.7
N.A.
51.7
N.A.
54.3
N.A.
Protein Similarity:
100
73.5
79.4
90.3
N.A.
79.4
79.1
N.A.
80.5
79.7
80.9
79.7
N.A.
69.5
N.A.
73.4
N.A.
P-Site Identity:
100
73.3
6.6
93.3
N.A.
66.6
73.3
N.A.
93.3
86.6
66.6
66.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
86.6
13.3
100
N.A.
93.3
86.6
N.A.
93.3
86.6
86.6
93.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
25
0
0
0
9
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% C
% Asp:
0
17
67
0
0
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
17
0
0
0
9
0
0
0
9
0
67
% E
% Phe:
17
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
0
0
0
0
17
75
0
% G
% His:
0
0
0
0
0
0
0
0
17
0
9
17
75
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
9
42
67
0
0
0
0
% I
% Lys:
0
0
0
0
67
0
0
0
0
0
17
0
0
0
17
% K
% Leu:
0
59
0
9
0
0
75
9
0
17
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
75
0
9
0
0
34
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
17
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
25
0
25
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
17
0
0
9
0
75
0
9
0
% T
% Val:
0
0
0
9
9
0
0
17
0
25
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
75
0
0
0
0
59
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _