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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYL5 All Species: 22.12
Human Site: S20 Identified Species: 44.24
UniProt: Q02045 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02045 NP_002468.1 173 19534 S20 A L R A Q R A S S N V F S N F
Chimpanzee Pan troglodytes XP_527844 193 21795 S41 K R A E G T A S S N V F S M F
Rhesus Macaque Macaca mulatta XP_001086310 190 20940 S20 A L R A Q R A S S N V F S N F
Dog Lupus familis XP_536281 186 20662 S33 G L R A Q R A S S N V F S N F
Cat Felis silvestris
Mouse Mus musculus Q9QVP4 175 19431 S22 T K Q A Q R G S S N V F S M F
Rat Rattus norvegicus P08733 166 18862 M20 G S S N V F S M F E Q T Q I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514366 206 23162 S53 G V R T Q K A S S S V F S N F
Chicken Gallus gallus P02611 165 18771 E21 S N V F S M F E Q T Q I Q E F
Frog Xenopus laevis NP_001087308 167 19067 M20 G S S N V F S M F E Q T Q I Q
Zebra Danio Brachydanio rerio NP_571404 172 19002 N20 T A Q R G S S N V F S M F E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40423 174 19936 T21 K K R A Q R A T S N V F A M F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09510 172 19922 V20 P Q R A T S N V F A M F D Q A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59 75.2 87 N.A. 63.4 62.4 N.A. 76.6 65.3 66.4 68.7 N.A. 51.7 N.A. 54.3 N.A.
Protein Similarity: 100 73.5 79.4 90.3 N.A. 79.4 79.1 N.A. 80.5 79.7 80.9 79.7 N.A. 69.5 N.A. 73.4 N.A.
P-Site Identity: 100 53.3 100 93.3 N.A. 66.6 0 N.A. 66.6 6.6 0 0 N.A. 66.6 N.A. 20 N.A.
P-Site Similarity: 100 53.3 100 93.3 N.A. 73.3 6.6 N.A. 86.6 13.3 6.6 20 N.A. 80 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 9 50 0 0 50 0 0 9 0 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 9 0 0 0 9 0 17 0 0 0 17 0 % E
% Phe: 0 0 0 9 0 17 9 0 25 9 0 67 9 0 67 % F
% Gly: 34 0 0 0 17 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 0 % I
% Lys: 17 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 17 0 0 9 9 0 25 0 % M
% Asn: 0 9 0 17 0 0 9 9 0 50 0 0 0 34 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 17 0 50 0 0 0 9 0 25 0 25 9 25 % Q
% Arg: 0 9 50 9 0 42 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 17 17 0 9 17 25 50 59 9 9 0 50 0 0 % S
% Thr: 17 0 0 9 9 9 0 9 0 9 0 17 0 0 0 % T
% Val: 0 9 9 0 17 0 0 9 9 0 59 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _