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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYL5 All Species: 21.21
Human Site: S25 Identified Species: 42.42
UniProt: Q02045 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02045 NP_002468.1 173 19534 S25 R A S S N V F S N F E Q T Q I
Chimpanzee Pan troglodytes XP_527844 193 21795 S46 T A S S N V F S M F D Q S Q I
Rhesus Macaque Macaca mulatta XP_001086310 190 20940 S25 R A S S N V F S N F E Q T Q I
Dog Lupus familis XP_536281 186 20662 S38 R A S S N V F S N F E Q T Q I
Cat Felis silvestris
Mouse Mus musculus Q9QVP4 175 19431 S27 R G S S N V F S M F E Q A Q I
Rat Rattus norvegicus P08733 166 18862 Q25 F S M F E Q T Q I Q E F K E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514366 206 23162 S58 K A S S S V F S N F E Q T Q I
Chicken Gallus gallus P02611 165 18771 Q26 M F E Q T Q I Q E F K E A F T
Frog Xenopus laevis NP_001087308 167 19067 Q25 F S M F E Q T Q I Q E F K E A
Zebra Danio Brachydanio rerio NP_571404 172 19002 F25 S S N V F S M F E Q S Q I Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40423 174 19936 A26 R A T S N V F A M F D Q A Q I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09510 172 19922 D25 S N V F A M F D Q A Q I Q E F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59 75.2 87 N.A. 63.4 62.4 N.A. 76.6 65.3 66.4 68.7 N.A. 51.7 N.A. 54.3 N.A.
Protein Similarity: 100 73.5 79.4 90.3 N.A. 79.4 79.1 N.A. 80.5 79.7 80.9 79.7 N.A. 69.5 N.A. 73.4 N.A.
P-Site Identity: 100 73.3 100 100 N.A. 80 6.6 N.A. 86.6 6.6 6.6 13.3 N.A. 66.6 N.A. 6.6 N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 80 20 N.A. 100 20 20 26.6 N.A. 86.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 0 0 9 0 0 9 0 9 0 0 25 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 0 0 17 0 0 0 0 % D
% Glu: 0 0 9 0 17 0 0 0 17 0 59 9 0 25 9 % E
% Phe: 17 9 0 25 9 0 67 9 0 67 0 17 0 9 9 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 17 0 0 9 9 0 59 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 9 0 17 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 9 0 17 0 0 9 9 0 25 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 50 0 0 0 34 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 25 0 25 9 25 9 67 9 67 0 % Q
% Arg: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 25 50 59 9 9 0 50 0 0 9 0 9 0 0 % S
% Thr: 9 0 9 0 9 0 17 0 0 0 0 0 34 0 9 % T
% Val: 0 0 9 9 0 59 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _