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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2A All Species: 33.33
Human Site: S255 Identified Species: 61.11
UniProt: Q02078 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02078 NP_001124398.1 507 54811 S255 G K V M P T K S P P P P G G G
Chimpanzee Pan troglodytes XP_001139086 503 54307 S255 G K V M P T K S P P P P G G G
Rhesus Macaque Macaca mulatta XP_001102710 505 54549 S255 G K V M P T K S P P P P G G G
Dog Lupus familis XP_858038 490 52717 S244 G K V M P T K S P P P P G G G
Cat Felis silvestris
Mouse Mus musculus Q60929 498 53560 S253 G K V M P T K S P P P P G G G
Rat Rattus norvegicus Q2MJT0 495 53235 S255 G K V M P T K S P P P P G G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507578 507 54968 S255 G K V M P T K S P P P P G G G
Chicken Gallus gallus Q9W6U8 499 53650 S254 G K V M P T K S P P P P G G G
Frog Xenopus laevis Q03414 516 56328 V286 L G P T G G N V L G K V M P T
Zebra Danio Brachydanio rerio NP_571376 460 49093 P230 N G L G K V M P A K S P P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S262 A P I P P N M S A P D D V G Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 L38 K A R E L S V L C D A E V A V
Baker's Yeast Sacchar. cerevisiae Q12224 676 73465 I437 F S A T Q P Y I A T P L Q P S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 94.6 N.A. 89.7 93.6 N.A. 93 83.2 79.2 70.6 N.A. 31.3 N.A. N.A. N.A.
Protein Similarity: 100 99.2 98.8 95.4 N.A. 92.9 95.4 N.A. 95.4 89.7 85.2 78.3 N.A. 46 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 6.6 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 13.3 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.2 21.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.2 36.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 0 0 24 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 62 16 0 8 8 8 0 0 0 8 0 0 62 70 62 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 8 62 0 0 8 0 62 0 0 8 8 0 0 0 0 % K
% Leu: 8 0 8 0 8 0 0 8 8 0 0 8 0 0 0 % L
% Met: 0 0 0 62 0 0 16 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 8 70 8 0 8 62 70 70 70 8 24 8 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 8 0 70 0 0 8 0 0 0 8 % S
% Thr: 0 0 0 16 0 62 0 0 0 8 0 0 0 0 8 % T
% Val: 0 0 62 0 0 8 8 8 0 0 0 8 16 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _