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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2B All Species: 15.15
Human Site: S168 Identified Species: 27.78
UniProt: Q02080 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02080 NP_005910.1 365 38639 S168 L P A Q S R P S P F R P A A P
Chimpanzee Pan troglodytes XP_512521 368 39108 S168 L P A Q S R P S P F R P A A P
Rhesus Macaque Macaca mulatta XP_001115695 368 39170 S168 L P A Q S R P S P F R P A A P
Dog Lupus familis XP_852158 417 45078 G235 P P G C D P S G L G E A L P A
Cat Felis silvestris
Mouse Mus musculus O55087 349 37416 G156 A T P G C D P G G L G E V P S
Rat Rattus norvegicus O89038 507 54350 A185 L L S P Q Q P A L Q R N S V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509613 423 45590 S167 G E P S P S Q S H P P P F K P
Chicken Gallus gallus Q9W6U8 499 53650 S163 N P G S S L V S P S L A A S S
Frog Xenopus laevis Q03414 516 56328 T214 L A A S A S L T D A R M L S P
Zebra Danio Brachydanio rerio XP_686335 420 46059 A181 V S A N S H P A L M G P H A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S180 T N I S P R P S S S E T D S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 Q93 E V D I L K D Q L S K L Q E K
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 G144 P L A S N D A G N A G V S T P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 72 61.8 N.A. 58.9 36.4 N.A. 54.1 33.8 32.9 38 N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 77.7 76.6 64.9 N.A. 66.8 46.3 N.A. 61.2 44.6 43.2 48 N.A. 41 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 6.6 20 N.A. 20 33.3 26.6 33.3 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 6.6 46.6 N.A. 20 40 46.6 46.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 23.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 47 0 8 0 8 16 0 16 0 16 31 31 8 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 8 16 8 0 8 0 0 0 8 0 0 % D
% Glu: 8 8 0 0 0 0 0 0 0 0 16 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 24 0 0 8 0 0 % F
% Gly: 8 0 16 8 0 0 0 24 8 8 24 0 0 0 16 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 8 0 0 8 8 % K
% Leu: 39 16 0 0 8 8 8 0 31 8 8 8 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 8 8 0 8 8 0 0 0 8 0 0 8 0 0 0 % N
% Pro: 16 39 16 8 16 8 54 0 31 8 8 39 0 16 47 % P
% Gln: 0 0 0 24 8 8 8 8 0 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 31 0 0 0 0 39 0 0 0 0 % R
% Ser: 0 8 8 39 39 16 8 47 8 24 0 0 16 24 24 % S
% Thr: 8 8 0 0 0 0 0 8 0 0 0 8 0 8 0 % T
% Val: 8 8 0 0 0 0 8 0 0 0 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _