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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2B All Species: 0.91
Human Site: S306 Identified Species: 1.67
UniProt: Q02080 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02080 NP_005910.1 365 38639 S306 P S P I P C S S P G P W Q S L
Chimpanzee Pan troglodytes XP_512521 368 39108 G303 G R S L G E E G P P T R G A S
Rhesus Macaque Macaca mulatta XP_001115695 368 39170 G303 G R S L G E E G P P T R G A S
Dog Lupus familis XP_852158 417 45078 A357 K G P P P R G A S P R T P Q L
Cat Felis silvestris
Mouse Mus musculus O55087 349 37416 G290 K E G P P S R G A S P P T P P
Rat Rattus norvegicus O89038 507 54350 P442 R S P A P P P P A V F P A A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509613 423 45590 H326 P A P G V S P H P Q P I S I K
Chicken Gallus gallus Q9W6U8 499 53650 S403 N Q N I N I K S E P I S P P R
Frog Xenopus laevis Q03414 516 56328 I431 S I N T N Q N I N I K S E P I
Zebra Danio Brachydanio rerio XP_686335 420 46059 P327 Q S S S P S S P S H P S L N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 A400 G G G G A V S A A N V I T H L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 T209 L Q N T D S D T T L Q L G L P
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 K387 R S K F L G F K N N D M D D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 72 61.8 N.A. 58.9 36.4 N.A. 54.1 33.8 32.9 38 N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 77.7 76.6 64.9 N.A. 66.8 46.3 N.A. 61.2 44.6 43.2 48 N.A. 41 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 20 N.A. 13.3 20 N.A. 26.6 13.3 0 33.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 20 26.6 N.A. 13.3 26.6 N.A. 33.3 13.3 20 40 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 23.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 0 16 24 0 0 0 8 24 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 0 0 8 0 8 8 0 % D
% Glu: 0 8 0 0 0 16 16 0 8 0 0 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 8 0 0 0 0 % F
% Gly: 24 16 16 16 16 8 8 24 0 8 0 0 24 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 8 0 0 0 8 0 % H
% Ile: 0 8 0 16 0 8 0 8 0 8 8 16 0 8 8 % I
% Lys: 16 0 8 0 0 0 8 8 0 0 8 0 0 0 8 % K
% Leu: 8 0 0 16 8 0 0 0 0 8 0 8 8 8 39 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 24 0 16 0 8 0 16 16 0 0 0 8 0 % N
% Pro: 16 0 31 16 39 8 16 16 31 31 31 16 16 24 16 % P
% Gln: 8 16 0 0 0 8 0 0 0 8 8 0 8 8 0 % Q
% Arg: 16 16 0 0 0 8 8 0 0 0 8 16 0 0 16 % R
% Ser: 8 31 24 8 0 31 24 16 16 8 0 24 8 8 16 % S
% Thr: 0 0 0 16 0 0 0 8 8 0 16 8 16 0 0 % T
% Val: 0 0 0 0 8 8 0 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _