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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2B All Species: 6.47
Human Site: S359 Identified Species: 11.87
UniProt: Q02080 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02080 NP_005910.1 365 38639 S359 D P T S L Q A S S E K T Q Q _
Chimpanzee Pan troglodytes XP_512521 368 39108 A356 E P L R P G P A L R R L P L A
Rhesus Macaque Macaca mulatta XP_001115695 368 39170 A356 E P L R P G P A L R R L P L A
Dog Lupus familis XP_852158 417 45078 I410 P P L P E F P I G N A W P R Y
Cat Felis silvestris
Mouse Mus musculus O55087 349 37416 T343 S A S L H R L T P D S W P R _
Rat Rattus norvegicus O89038 507 54350 A495 E P E A E G S A V K R M R L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509613 423 45590 R379 P Y P L V L A R P L N E E P R
Chicken Gallus gallus Q9W6U8 499 53650 S456 S L S S S S S S Y D G S D R E
Frog Xenopus laevis Q03414 516 56328 N484 S D R E D V R N D F H S P I G
Zebra Danio Brachydanio rerio XP_686335 420 46059 Q380 S D E Y A D L Q R E E A Q K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 P453 Q Q H H L G M P N S R P S S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 K262 A N S P P E A K R Q R F S V _
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 S440 F P S S V A S S T L K S T S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 72 61.8 N.A. 58.9 36.4 N.A. 54.1 33.8 32.9 38 N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 77.7 76.6 64.9 N.A. 66.8 46.3 N.A. 61.2 44.6 43.2 48 N.A. 41 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 0 6.6 N.A. 6.6 13.3 0 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 26.6 20 N.A. 35.7 53.3 N.A. 20 46.6 20 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 23.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. 7.1 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 35.7 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 8 8 24 24 0 0 8 8 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 16 0 0 8 8 0 0 8 16 0 0 8 0 8 % D
% Glu: 24 0 16 8 16 8 0 0 0 16 8 8 8 0 8 % E
% Phe: 8 0 0 0 0 8 0 0 0 8 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 31 0 0 8 0 8 0 0 0 8 % G
% His: 0 0 8 8 8 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 8 16 0 0 8 0 % K
% Leu: 0 8 24 16 16 8 16 0 16 16 0 16 0 24 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 8 8 8 0 0 0 0 % N
% Pro: 16 47 8 16 24 0 24 8 16 0 0 8 39 8 0 % P
% Gln: 8 8 0 0 0 8 0 8 0 8 0 0 16 8 0 % Q
% Arg: 0 0 8 16 0 8 8 8 16 16 39 0 8 24 8 % R
% Ser: 31 0 31 24 8 8 24 24 8 8 8 24 16 16 16 % S
% Thr: 0 0 8 0 0 0 0 8 8 0 0 8 8 0 8 % T
% Val: 0 0 0 0 16 8 0 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 % _