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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2B All Species: 6.36
Human Site: T295 Identified Species: 11.67
UniProt: Q02080 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02080 NP_005910.1 365 38639 T295 R P P G A P A T F L R P S P I
Chimpanzee Pan troglodytes XP_512521 368 39108 Q292 G P P A V P S Q P S G G R S L
Rhesus Macaque Macaca mulatta XP_001115695 368 39170 Q292 G P P A V P S Q P S G G R S L
Dog Lupus familis XP_852158 417 45078 T346 P Q P S G A Q T L I K K G P P
Cat Felis silvestris
Mouse Mus musculus O55087 349 37416 R279 D P A R P V A R S L C K E G P
Rat Rattus norvegicus O89038 507 54350 P431 I K S E P V S P S R E R S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509613 423 45590 D315 A A R I P P G D E G P P A P G
Chicken Gallus gallus Q9W6U8 499 53650 S392 L S Q G S N L S I N T N Q N I
Frog Xenopus laevis Q03414 516 56328 G420 A T G Q L S Q G S N L S I N T
Zebra Danio Brachydanio rerio XP_686335 420 46059 S316 M A S G G S C S Y P S Q S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S389 S S T S S N A S G G A G G G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 S198 N A L I N H D S K C S L Q N T
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 S376 M L A S N M S S P L S R S K F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 72 61.8 N.A. 58.9 36.4 N.A. 54.1 33.8 32.9 38 N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 77.7 76.6 64.9 N.A. 66.8 46.3 N.A. 61.2 44.6 43.2 48 N.A. 41 N.A. N.A. N.A.
P-Site Identity: 100 20 20 20 N.A. 20 13.3 N.A. 20 13.3 0 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 33.3 33.3 N.A. 20 20 N.A. 26.6 26.6 0 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 23.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 24 16 16 8 8 24 0 0 0 8 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 8 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 16 0 8 24 16 0 8 8 8 16 16 24 16 16 16 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 16 0 0 0 0 8 8 0 0 8 0 16 % I
% Lys: 0 8 0 0 0 0 0 0 8 0 8 16 0 8 0 % K
% Leu: 8 8 8 0 8 0 8 0 8 24 8 8 0 0 16 % L
% Met: 16 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 16 16 0 0 0 16 0 8 0 24 0 % N
% Pro: 8 31 31 0 24 31 0 8 24 8 8 16 0 31 16 % P
% Gln: 0 8 8 8 0 0 16 16 0 0 0 8 16 0 0 % Q
% Arg: 8 0 8 8 0 0 0 8 0 8 8 16 16 0 0 % R
% Ser: 8 16 16 24 16 16 31 39 24 16 24 8 31 24 8 % S
% Thr: 0 8 8 0 0 0 0 16 0 0 8 0 0 0 16 % T
% Val: 0 0 0 0 16 16 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _