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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2B All Species: 13.64
Human Site: Y131 Identified Species: 25
UniProt: Q02080 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02080 NP_005910.1 365 38639 Y131 A L P R P R L Y P A A P A M P
Chimpanzee Pan troglodytes XP_512521 368 39108 Y131 A L P R P R L Y P A A P A M P
Rhesus Macaque Macaca mulatta XP_001115695 368 39170 Y131 A L P R P R L Y P A A P A M P
Dog Lupus familis XP_852158 417 45078 D198 K L R R L A G D G G D P A L P
Cat Felis silvestris
Mouse Mus musculus O55087 349 37416 G119 K L L R T L G G D R G S A S P
Rat Rattus norvegicus O89038 507 54350 V148 A M P V T V P V S N Q S S M Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509613 423 45590 Y130 S L T R Q R L Y S A A P P L P
Chicken Gallus gallus Q9W6U8 499 53650 F126 N E D S D F I F K R G P P G L
Frog Xenopus laevis Q03414 516 56328 Q177 I S P G L P Q Q T F P M S V T
Zebra Danio Brachydanio rerio XP_686335 420 46059 G144 I N T S A E N G Y I N S S N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 P143 A G A P R Q L P N S S Y T L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 E56 S K S G K L F E Y S S T G M K
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 T107 K R R R R R A T V L Q P A S H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 72 61.8 N.A. 58.9 36.4 N.A. 54.1 33.8 32.9 38 N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 77.7 76.6 64.9 N.A. 66.8 46.3 N.A. 61.2 44.6 43.2 48 N.A. 41 N.A. N.A. N.A.
P-Site Identity: 100 100 100 33.3 N.A. 26.6 20 N.A. 60 6.6 6.6 6.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 26.6 33.3 N.A. 73.3 20 20 13.3 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 23.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 8 0 8 8 8 0 0 31 31 0 47 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 8 0 0 8 8 0 8 0 0 0 0 % D
% Glu: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 8 8 0 8 0 0 0 0 0 % F
% Gly: 0 8 0 16 0 0 16 16 8 8 16 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 16 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % I
% Lys: 24 8 0 0 8 0 0 0 8 0 0 0 0 0 8 % K
% Leu: 0 47 8 0 16 16 39 0 0 8 0 0 0 24 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 8 0 39 0 % M
% Asn: 8 8 0 0 0 0 8 0 8 8 8 0 0 8 0 % N
% Pro: 0 0 39 8 24 8 8 8 24 0 8 54 16 0 62 % P
% Gln: 0 0 0 0 8 8 8 8 0 0 16 0 0 0 8 % Q
% Arg: 0 8 16 54 16 39 0 0 0 16 0 0 0 0 0 % R
% Ser: 16 8 8 16 0 0 0 0 16 16 16 24 24 16 0 % S
% Thr: 0 0 16 0 16 0 0 8 8 0 0 8 8 0 8 % T
% Val: 0 0 0 8 0 8 0 8 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 31 16 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _