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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2B
All Species:
45.45
Human Site:
Y69
Identified Species:
83.33
UniProt:
Q02080
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02080
NP_005910.1
365
38639
Y69
M
D
R
V
L
L
K
Y
T
E
Y
S
E
P
H
Chimpanzee
Pan troglodytes
XP_512521
368
39108
Y69
M
D
R
V
L
L
K
Y
T
E
Y
S
E
P
H
Rhesus Macaque
Macaca mulatta
XP_001115695
368
39170
Y69
M
D
R
V
L
L
K
Y
T
E
Y
S
E
P
H
Dog
Lupus familis
XP_852158
417
45078
Y148
M
D
R
V
L
L
K
Y
T
E
Y
S
E
P
H
Cat
Felis silvestris
Mouse
Mus musculus
O55087
349
37416
Y69
M
D
R
V
L
L
K
Y
T
E
Y
S
E
P
H
Rat
Rattus norvegicus
O89038
507
54350
Y69
M
D
K
V
L
L
K
Y
T
E
Y
N
E
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509613
423
45590
Y69
M
D
K
V
L
L
K
Y
T
E
Y
S
E
P
H
Chicken
Gallus gallus
Q9W6U8
499
53650
Y69
M
D
K
V
L
L
K
Y
T
E
Y
N
E
P
H
Frog
Xenopus laevis
Q03414
516
56328
Y69
M
D
K
V
L
L
K
Y
T
E
Y
N
E
P
H
Zebra Danio
Brachydanio rerio
XP_686335
420
46059
Y69
M
D
K
V
L
L
K
Y
T
E
Y
S
E
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
Y69
M
D
R
V
L
L
K
Y
T
E
Y
N
E
P
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
K23
S
R
Q
V
T
F
S
K
R
R
S
G
L
L
K
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
H69
M
S
N
L
L
N
V
H
Q
N
N
T
D
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.6
72
61.8
N.A.
58.9
36.4
N.A.
54.1
33.8
32.9
38
N.A.
32.2
N.A.
N.A.
N.A.
Protein Similarity:
100
77.7
76.6
64.9
N.A.
66.8
46.3
N.A.
61.2
44.6
43.2
48
N.A.
41
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
93.3
86.6
86.6
93.3
N.A.
93.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
36.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
85
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
85
0
0
85
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
85
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
39
0
0
0
85
8
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
8
93
85
0
0
0
0
0
0
8
16
0
% L
% Met:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
8
31
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
85
8
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
47
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
8
0
0
0
8
54
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
85
0
0
8
0
0
0
% T
% Val:
0
0
0
93
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
85
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _