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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHODH
All Species:
51.52
Human Site:
S150
Identified Species:
75.56
UniProt:
Q02127
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02127
NP_001352.2
395
42867
S150
I
N
R
Y
G
F
N
S
H
G
L
S
V
V
E
Chimpanzee
Pan troglodytes
XP_001171601
395
42934
S150
I
N
R
Y
G
F
N
S
H
G
L
S
V
V
E
Rhesus Macaque
Macaca mulatta
XP_001104448
395
42761
S150
I
N
R
Y
G
F
N
S
H
G
L
S
V
V
E
Dog
Lupus familis
XP_853399
414
44435
S169
I
N
R
Y
G
F
N
S
H
G
L
S
V
V
E
Cat
Felis silvestris
Mouse
Mus musculus
O35435
395
42682
S150
I
N
R
Y
G
F
N
S
H
G
L
S
A
V
E
Rat
Rattus norvegicus
Q63707
395
42644
S150
I
N
R
Y
G
F
N
S
H
G
L
S
V
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505402
311
33595
T93
Q
Q
K
Q
I
K
L
T
E
D
G
M
P
L
G
Chicken
Gallus gallus
NP_001006131
387
41379
S142
I
N
R
Y
G
F
N
S
H
G
H
A
A
V
E
Frog
Xenopus laevis
NP_001085026
404
43603
S150
I
N
R
Y
G
F
N
S
H
G
V
E
I
V
Q
Zebra Danio
Brachydanio rerio
NP_001008608
407
43839
S149
I
N
R
Y
G
F
N
S
C
G
L
S
A
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32748
405
44323
R153
E
D
K
A
I
I
N
R
Y
G
F
N
S
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491930
411
45667
S163
I
N
R
Y
G
F
N
S
D
G
V
G
R
V
H
Sea Urchin
Strong. purpuratus
XP_794275
377
40637
S146
I
N
R
Y
G
F
N
S
V
G
H
D
V
V
H
Poplar Tree
Populus trichocarpa
XP_002306374
457
48689
S193
I
N
R
C
G
F
N
S
E
G
I
V
A
V
A
Maize
Zea mays
NP_001152058
469
49529
S205
I
N
R
C
G
F
N
S
E
G
I
V
V
V
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P32746
460
48528
S196
I
N
R
C
G
F
N
S
E
G
I
V
V
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
84.5
N.A.
87.5
88.6
N.A.
65.8
72.6
66.3
66.3
N.A.
47.9
N.A.
49.6
56.2
Protein Similarity:
100
99.7
98.9
88.8
N.A.
92.6
93.4
N.A.
73.1
81.2
82.4
79.6
N.A.
64.6
N.A.
66.9
73.1
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
80
73.3
80
N.A.
13.3
N.A.
66.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
20
86.6
93.3
80
N.A.
40
N.A.
73.3
73.3
Percent
Protein Identity:
45
47.1
N.A.
46.9
N.A.
N.A.
Protein Similarity:
61.2
60.9
N.A.
61.3
N.A.
N.A.
P-Site Identity:
60
66.6
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
66.6
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
7
25
0
19
% A
% Cys:
0
0
0
19
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
7
7
0
7
0
7
0
% D
% Glu:
7
0
0
0
0
0
0
0
25
0
0
7
0
0
44
% E
% Phe:
0
0
0
0
0
88
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
88
0
0
0
0
94
7
7
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
50
0
13
0
0
0
19
% H
% Ile:
88
0
0
0
13
7
0
0
0
0
19
0
7
0
0
% I
% Lys:
0
0
13
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
44
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
88
0
0
0
0
94
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
7
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
88
0
0
0
0
7
0
0
0
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
88
0
0
0
44
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
7
0
13
19
50
88
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
69
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _