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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHODH
All Species:
32.42
Human Site:
S298
Identified Species:
47.56
UniProt:
Q02127
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02127
NP_001352.2
395
42867
S298
G
L
Q
G
A
L
R
S
E
T
G
G
L
S
G
Chimpanzee
Pan troglodytes
XP_001171601
395
42934
S298
G
L
Q
G
A
L
R
S
E
T
G
G
L
S
G
Rhesus Macaque
Macaca mulatta
XP_001104448
395
42761
S298
G
L
Q
G
A
L
R
S
E
T
G
G
L
S
G
Dog
Lupus familis
XP_853399
414
44435
S317
S
L
Q
G
A
L
R
S
E
I
G
G
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
O35435
395
42682
S298
G
L
Q
G
A
L
R
S
E
T
G
G
L
S
G
Rat
Rattus norvegicus
Q63707
395
42644
S298
G
L
Q
G
A
L
R
S
E
T
G
G
L
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505402
311
33595
K228
E
T
G
G
L
S
G
K
P
L
R
A
L
A
T
Chicken
Gallus gallus
NP_001006131
387
41379
L290
G
L
Q
S
T
Q
R
L
E
A
G
G
L
S
G
Frog
Xenopus laevis
NP_001085026
404
43603
S298
S
L
Q
D
P
Q
S
S
E
V
G
G
L
S
G
Zebra Danio
Brachydanio rerio
NP_001008608
407
43839
V297
T
L
K
D
P
N
R
V
E
T
G
G
L
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32748
405
44323
E304
I
E
K
N
K
L
A
E
E
T
G
G
L
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491930
411
45667
T311
Y
L
R
S
E
N
K
T
E
T
G
G
L
S
G
Sea Urchin
Strong. purpuratus
XP_794275
377
40637
T284
G
I
I
V
T
N
T
T
I
T
R
P
E
S
L
Poplar Tree
Populus trichocarpa
XP_002306374
457
48689
E361
V
N
K
S
P
V
A
E
E
T
G
G
L
S
G
Maize
Zea mays
NP_001152058
469
49529
Q373
A
D
K
H
P
L
A
Q
E
T
G
G
L
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P32746
460
48528
T364
V
S
N
N
P
V
A
T
E
T
G
G
L
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
84.5
N.A.
87.5
88.6
N.A.
65.8
72.6
66.3
66.3
N.A.
47.9
N.A.
49.6
56.2
Protein Similarity:
100
99.7
98.9
88.8
N.A.
92.6
93.4
N.A.
73.1
81.2
82.4
79.6
N.A.
64.6
N.A.
66.9
73.1
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
13.3
66.6
60
60
N.A.
53.3
N.A.
53.3
20
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
20
66.6
60
66.6
N.A.
60
N.A.
73.3
33.3
Percent
Protein Identity:
45
47.1
N.A.
46.9
N.A.
N.A.
Protein Similarity:
61.2
60.9
N.A.
61.3
N.A.
N.A.
P-Site Identity:
46.6
53.3
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
60
60
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
38
0
25
0
0
7
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
7
0
0
7
0
0
13
88
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
44
0
7
44
0
0
7
0
0
0
88
88
0
0
88
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
7
0
0
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
0
0
25
0
7
0
7
7
0
0
0
0
0
0
0
% K
% Leu:
0
63
0
0
7
50
0
7
0
7
0
0
94
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
13
0
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
32
0
0
0
7
0
0
7
0
0
0
% P
% Gln:
0
0
50
0
0
13
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
50
0
0
0
13
0
0
0
0
% R
% Ser:
13
7
0
19
0
7
7
44
0
0
0
0
0
94
0
% S
% Thr:
7
7
0
0
13
0
7
19
0
75
0
0
0
0
7
% T
% Val:
13
0
0
7
0
13
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _