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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHODH
All Species:
24.85
Human Site:
S75
Identified Species:
36.44
UniProt:
Q02127
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02127
NP_001352.2
395
42867
S75
P
R
A
R
F
Q
D
S
D
M
L
E
V
R
V
Chimpanzee
Pan troglodytes
XP_001171601
395
42934
S75
P
R
A
R
F
Q
D
S
D
M
L
E
V
R
V
Rhesus Macaque
Macaca mulatta
XP_001104448
395
42761
S75
P
R
A
R
F
Q
D
S
D
M
L
E
V
R
V
Dog
Lupus familis
XP_853399
414
44435
S94
P
R
A
T
F
Q
E
S
D
M
L
E
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
O35435
395
42682
S75
P
R
A
T
F
Q
D
S
N
M
L
E
V
R
V
Rat
Rattus norvegicus
Q63707
395
42644
S75
P
R
A
T
F
Q
D
S
D
M
L
E
V
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505402
311
33595
P46
V
G
S
V
T
P
K
P
Q
E
G
N
P
R
P
Chicken
Gallus gallus
NP_001006131
387
41379
P68
P
P
A
R
P
D
S
P
S
L
E
V
H
V
L
Frog
Xenopus laevis
NP_001085026
404
43603
S75
P
L
C
K
H
H
N
S
E
R
L
E
V
K
V
Zebra Danio
Brachydanio rerio
NP_001008608
407
43839
P74
P
R
N
N
Y
K
D
P
T
S
L
E
V
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32748
405
44323
D83
P
V
S
Q
Y
H
D
D
Q
N
L
H
T
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491930
411
45667
K85
P
R
F
G
W
N
R
K
E
Y
P
E
L
K
C
Sea Urchin
Strong. purpuratus
XP_794275
377
40637
P71
P
R
S
K
Y
K
D
P
P
I
L
H
C
K
A
Poplar Tree
Populus trichocarpa
XP_002306374
457
48689
P118
P
R
E
K
R
P
D
P
S
V
L
G
L
E
V
Maize
Zea mays
NP_001152058
469
49529
P130
P
R
E
K
R
P
D
P
S
V
L
G
V
E
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P32746
460
48528
P121
P
R
E
K
R
P
D
P
A
I
L
G
L
E
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
84.5
N.A.
87.5
88.6
N.A.
65.8
72.6
66.3
66.3
N.A.
47.9
N.A.
49.6
56.2
Protein Similarity:
100
99.7
98.9
88.8
N.A.
92.6
93.4
N.A.
73.1
81.2
82.4
79.6
N.A.
64.6
N.A.
66.9
73.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
6.6
20
40
46.6
N.A.
20
N.A.
20
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
33.3
66.6
60
N.A.
40
N.A.
46.6
66.6
Percent
Protein Identity:
45
47.1
N.A.
46.9
N.A.
N.A.
Protein Similarity:
61.2
60.9
N.A.
61.3
N.A.
N.A.
P-Site Identity:
33.3
40
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
53.3
53.3
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
44
0
0
0
0
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
0
0
0
0
7
69
7
32
0
0
0
0
0
0
% D
% Glu:
0
0
19
0
0
0
7
0
13
7
7
57
0
19
0
% E
% Phe:
0
0
7
0
38
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
7
19
0
0
0
% G
% His:
0
0
0
0
7
13
0
0
0
0
0
13
7
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
32
0
13
7
7
0
0
0
0
0
25
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
7
82
0
19
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
38
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
7
7
0
7
7
0
7
0
0
0
% N
% Pro:
94
7
0
0
7
25
0
44
7
0
7
0
7
0
7
% P
% Gln:
0
0
0
7
0
38
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
75
0
25
19
0
7
0
0
7
0
0
0
38
0
% R
% Ser:
0
0
19
0
0
0
7
44
19
7
0
0
0
7
0
% S
% Thr:
0
0
0
19
7
0
0
0
7
0
0
0
7
0
0
% T
% Val:
7
7
0
7
0
0
0
0
0
13
0
7
57
7
69
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _