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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHODH All Species: 57.27
Human Site: T313 Identified Species: 84
UniProt: Q02127 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02127 NP_001352.2 395 42867 T313 K P L R D L S T Q T I R E M Y
Chimpanzee Pan troglodytes XP_001171601 395 42934 T313 K P L R D L S T Q T I R E M Y
Rhesus Macaque Macaca mulatta XP_001104448 395 42761 T313 K P L R D L S T Q T I R E M Y
Dog Lupus familis XP_853399 414 44435 T332 K P L R D L S T Q T I R E M Y
Cat Felis silvestris
Mouse Mus musculus O35435 395 42682 T313 K P L R D L S T Q T I R E M Y
Rat Rattus norvegicus Q63707 395 42644 T313 K P L R D L S T Q T I R E M Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505402 311 33595 S243 Q T V S E M Y S L T Q G Q V P
Chicken Gallus gallus NP_001006131 387 41379 T305 K P L R E L S T Q T V R E M Y
Frog Xenopus laevis NP_001085026 404 43603 T313 A P L R D L A T E T V R E M Y
Zebra Danio Brachydanio rerio NP_001008608 407 43839 T312 Q P L K E L S T Q T V R E M Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32748 405 44323 T319 P P L K A R S T E M I A Q M Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491930 411 45667 T326 A P V R E I S T E C V R K I Y
Sea Urchin Strong. purpuratus XP_794275 377 40637 T299 E G K H K G E T G G L S G V P
Poplar Tree Populus trichocarpa XP_002306374 457 48689 T376 K P L L N L S T N I L K E M F
Maize Zea mays NP_001152058 469 49529 T388 K P L L D L S T N I L R D M Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P32746 460 48528 T379 K P L F A L S T N M L R D M Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.9 84.5 N.A. 87.5 88.6 N.A. 65.8 72.6 66.3 66.3 N.A. 47.9 N.A. 49.6 56.2
Protein Similarity: 100 99.7 98.9 88.8 N.A. 92.6 93.4 N.A. 73.1 81.2 82.4 79.6 N.A. 64.6 N.A. 66.9 73.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 86.6 73.3 73.3 N.A. 46.6 N.A. 40 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 53.3 100 93.3 100 N.A. 66.6 N.A. 86.6 26.6
Percent
Protein Identity: 45 47.1 N.A. 46.9 N.A. N.A.
Protein Similarity: 61.2 60.9 N.A. 61.3 N.A. N.A.
P-Site Identity: 53.3 66.6 N.A. 60 N.A. N.A.
P-Site Similarity: 80 80 N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 13 0 7 0 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 0 0 0 0 0 0 13 0 0 % D
% Glu: 7 0 0 0 25 0 7 0 19 0 0 0 63 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 7 0 0 0 7 0 0 7 7 0 7 7 0 0 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 13 44 0 0 7 0 % I
% Lys: 63 0 7 13 7 0 0 0 0 0 0 7 7 0 0 % K
% Leu: 0 0 82 13 0 75 0 0 7 0 25 0 0 0 0 % L
% Met: 0 0 0 0 0 7 0 0 0 13 0 0 0 82 0 % M
% Asn: 0 0 0 0 7 0 0 0 19 0 0 0 0 0 0 % N
% Pro: 7 88 0 0 0 0 0 0 0 0 0 0 0 0 13 % P
% Gln: 13 0 0 0 0 0 0 0 50 0 7 0 13 0 0 % Q
% Arg: 0 0 0 57 0 7 0 0 0 0 0 75 0 0 0 % R
% Ser: 0 0 0 7 0 0 82 7 0 0 0 7 0 0 0 % S
% Thr: 0 7 0 0 0 0 0 94 0 63 0 0 0 0 0 % T
% Val: 0 0 13 0 0 0 0 0 0 0 25 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 82 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _