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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHODH
All Species:
47.58
Human Site:
Y194
Identified Species:
69.78
UniProt:
Q02127
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02127
NP_001352.2
395
42867
Y194
S
V
D
A
A
E
D
Y
A
E
G
V
R
V
L
Chimpanzee
Pan troglodytes
XP_001171601
395
42934
Y194
S
V
D
A
A
E
D
Y
A
E
G
V
R
V
L
Rhesus Macaque
Macaca mulatta
XP_001104448
395
42761
Y194
S
V
D
A
A
E
D
Y
A
E
G
V
R
V
L
Dog
Lupus familis
XP_853399
414
44435
Y213
S
V
D
A
A
A
D
Y
T
E
G
V
R
V
L
Cat
Felis silvestris
Mouse
Mus musculus
O35435
395
42682
Y194
S
V
D
A
A
A
D
Y
V
E
G
V
R
I
L
Rat
Rattus norvegicus
Q63707
395
42644
Y194
S
E
D
A
A
A
D
Y
A
E
G
V
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505402
311
33595
S135
D
Y
L
V
V
N
V
S
S
P
N
T
A
G
L
Chicken
Gallus gallus
NP_001006131
387
41379
Y186
S
T
D
A
A
A
D
Y
V
A
G
V
Q
T
L
Frog
Xenopus laevis
NP_001085026
404
43603
Y194
S
E
D
A
A
A
D
Y
T
Q
G
L
Q
Q
L
Zebra Danio
Brachydanio rerio
NP_001008608
407
43839
Y193
S
P
D
A
V
S
D
Y
V
E
G
V
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32748
405
44323
Y198
T
M
S
P
I
A
D
Y
V
Q
G
V
R
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491930
411
45667
Y205
T
E
D
A
K
L
D
Y
E
I
G
V
N
Y
F
Sea Urchin
Strong. purpuratus
XP_794275
377
40637
Y191
S
P
S
A
V
Q
D
Y
V
D
G
V
K
K
L
Poplar Tree
Populus trichocarpa
XP_002306374
457
48689
Y254
S
E
D
A
A
A
D
Y
V
Q
G
V
H
S
L
Maize
Zea mays
NP_001152058
469
49529
Y266
S
E
D
A
A
A
D
Y
V
Q
G
V
H
T
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P32746
460
48528
Y257
S
E
D
A
A
A
D
Y
V
Q
G
V
H
N
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
84.5
N.A.
87.5
88.6
N.A.
65.8
72.6
66.3
66.3
N.A.
47.9
N.A.
49.6
56.2
Protein Similarity:
100
99.7
98.9
88.8
N.A.
92.6
93.4
N.A.
73.1
81.2
82.4
79.6
N.A.
64.6
N.A.
66.9
73.1
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
60
53.3
66.6
N.A.
40
N.A.
40
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
80
N.A.
13.3
66.6
73.3
66.6
N.A.
60
N.A.
46.6
66.6
Percent
Protein Identity:
45
47.1
N.A.
46.9
N.A.
N.A.
Protein Similarity:
61.2
60.9
N.A.
61.3
N.A.
N.A.
P-Site Identity:
60
60
N.A.
60
N.A.
N.A.
P-Site Similarity:
66.6
66.6
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
88
69
57
0
0
25
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
82
0
0
0
94
0
0
7
0
0
0
0
0
% D
% Glu:
0
38
0
0
0
19
0
0
7
44
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
94
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
7
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
0
% K
% Leu:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
88
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
7
0
7
7
0
% N
% Pro:
0
13
0
7
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
32
0
0
13
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% R
% Ser:
82
0
13
0
0
7
0
7
7
0
0
0
0
7
0
% S
% Thr:
13
7
0
0
0
0
0
0
13
0
0
7
0
25
0
% T
% Val:
0
32
0
7
19
0
7
0
50
0
0
88
0
32
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
94
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _