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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHODH
All Species:
49.39
Human Site:
Y320
Identified Species:
72.44
UniProt:
Q02127
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02127
NP_001352.2
395
42867
Y320
T
Q
T
I
R
E
M
Y
A
L
T
Q
G
R
V
Chimpanzee
Pan troglodytes
XP_001171601
395
42934
Y320
T
Q
T
I
R
E
M
Y
A
L
T
Q
G
R
V
Rhesus Macaque
Macaca mulatta
XP_001104448
395
42761
Y320
T
Q
T
I
R
E
M
Y
A
L
T
Q
G
R
V
Dog
Lupus familis
XP_853399
414
44435
Y339
T
Q
T
I
R
E
M
Y
A
L
T
Q
G
G
V
Cat
Felis silvestris
Mouse
Mus musculus
O35435
395
42682
Y320
T
Q
T
I
R
E
M
Y
A
L
T
Q
G
T
I
Rat
Rattus norvegicus
Q63707
395
42644
Y320
T
Q
T
I
R
E
M
Y
A
L
T
Q
G
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505402
311
33595
P250
S
L
T
Q
G
Q
V
P
I
I
G
V
G
G
I
Chicken
Gallus gallus
NP_001006131
387
41379
Y312
T
Q
T
V
R
E
M
Y
A
L
T
Q
G
R
V
Frog
Xenopus laevis
NP_001085026
404
43603
Y320
T
E
T
V
R
E
M
Y
A
L
T
A
G
K
I
Zebra Danio
Brachydanio rerio
NP_001008608
407
43839
Y319
T
Q
T
V
R
E
M
Y
T
L
T
Q
G
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32748
405
44323
Y326
T
E
M
I
A
Q
M
Y
Q
L
T
D
G
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491930
411
45667
Y333
T
E
C
V
R
K
I
Y
K
L
T
N
G
Q
I
Sea Urchin
Strong. purpuratus
XP_794275
377
40637
P306
T
G
G
L
S
G
V
P
L
K
D
M
S
T
A
Poplar Tree
Populus trichocarpa
XP_002306374
457
48689
F383
T
N
I
L
K
E
M
F
I
L
T
R
G
K
I
Maize
Zea mays
NP_001152058
469
49529
Y395
T
N
I
L
R
D
M
Y
M
L
T
R
G
K
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P32746
460
48528
Y386
T
N
M
L
R
D
M
Y
T
L
T
R
G
K
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
84.5
N.A.
87.5
88.6
N.A.
65.8
72.6
66.3
66.3
N.A.
47.9
N.A.
49.6
56.2
Protein Similarity:
100
99.7
98.9
88.8
N.A.
92.6
93.4
N.A.
73.1
81.2
82.4
79.6
N.A.
64.6
N.A.
66.9
73.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
13.3
93.3
66.6
73.3
N.A.
46.6
N.A.
40
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
46.6
100
93.3
93.3
N.A.
73.3
N.A.
80
20
Percent
Protein Identity:
45
47.1
N.A.
46.9
N.A.
N.A.
Protein Similarity:
61.2
60.9
N.A.
61.3
N.A.
N.A.
P-Site Identity:
40
46.6
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
80
80
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
50
0
0
7
0
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
0
7
7
0
0
0
% D
% Glu:
0
19
0
0
0
63
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
7
7
0
0
0
0
7
0
94
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
44
0
0
7
0
13
7
0
0
0
0
57
% I
% Lys:
0
0
0
0
7
7
0
0
7
7
0
0
0
38
0
% K
% Leu:
0
7
0
25
0
0
0
0
7
88
0
0
0
0
7
% L
% Met:
0
0
13
0
0
0
82
0
7
0
0
7
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
50
0
7
0
13
0
0
7
0
0
50
0
7
0
% Q
% Arg:
0
0
0
0
75
0
0
0
0
0
0
19
0
32
0
% R
% Ser:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% S
% Thr:
94
0
63
0
0
0
0
0
13
0
88
0
0
13
0
% T
% Val:
0
0
0
25
0
0
13
0
0
0
0
7
0
0
32
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _