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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCY1B3
All Species:
0
Human Site:
S119
Identified Species:
0
UniProt:
Q02153
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02153
NP_000848.1
619
70514
S119
Y
P
G
M
R
A
P
S
F
R
C
T
D
A
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O54865
620
70579
Rat
Rattus norvegicus
P20595
619
70438
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510819
683
77917
Chicken
Gallus gallus
XP_420376
698
78758
Frog
Xenopus laevis
NP_001085192
609
69543
Zebra Danio
Brachydanio rerio
XP_001920263
608
69179
Tiger Blowfish
Takifugu rubipres
NP_001027728
617
70218
Fruit Fly
Dros. melanogaster
Q8INF0
947
105028
Honey Bee
Apis mellifera
NP_001011632
603
68286
Nematode Worm
Caenorhab. elegans
Q6DNF4
675
76632
Sea Urchin
Strong. purpuratus
P16065
1125
126238
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
98.7
98.8
N.A.
88.2
85.8
93.6
88
87.4
24.2
63.8
32.2
20.1
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.3
99.5
N.A.
89.5
86.9
96.2
93.6
94
38.6
77.7
52.4
32.5
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
0
0
0
0
0
0
0
0
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
0
0
0
0
0
0
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
100
0
0
0
0
0
0
0
100
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
100
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
100
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _