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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OGDH
All Species:
43.64
Human Site:
S274
Identified Species:
80
UniProt:
Q02218
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02218
NP_001003941.1
1023
115935
S274
F
L
Q
R
K
W
S
S
E
K
R
F
G
L
E
Chimpanzee
Pan troglodytes
XP_001146956
1023
115904
S274
F
L
Q
R
K
W
S
S
E
K
R
F
G
L
E
Rhesus Macaque
Macaca mulatta
XP_001089063
1023
115873
S274
F
L
Q
R
K
W
S
S
E
K
R
F
G
L
E
Dog
Lupus familis
XP_532722
881
99572
E216
Q
W
I
R
Q
K
F
E
T
P
G
I
M
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60597
1023
116430
S274
F
L
Q
R
K
W
S
S
E
K
R
F
G
L
E
Rat
Rattus norvegicus
Q5XI78
1023
116277
S274
F
L
Q
R
K
W
S
S
E
K
R
F
G
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509039
937
105661
S269
F
L
A
R
K
W
S
S
E
K
R
F
G
L
E
Chicken
Gallus gallus
NP_001026553
1016
115163
S269
F
L
H
R
K
W
S
S
E
K
R
F
G
L
E
Frog
Xenopus laevis
Q6P6Z8
1021
115614
S273
F
L
H
R
K
W
S
S
E
K
R
F
G
L
E
Zebra Danio
Brachydanio rerio
NP_957073
1022
115620
S274
F
L
Q
R
K
W
S
S
E
K
R
F
G
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391838
1029
116125
S290
F
L
A
R
K
W
S
S
E
K
R
F
G
L
E
Nematode Worm
Caenorhab. elegans
O61199
1029
115643
S279
F
L
A
K
K
W
P
S
E
K
R
F
G
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20967
1014
114398
N268
F
L
S
T
K
F
P
N
D
K
R
F
G
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.9
80.4
N.A.
95.8
96.2
N.A.
73
91.4
90.1
86.5
N.A.
N.A.
65.1
56.1
N.A.
Protein Similarity:
100
99.9
99.9
82.4
N.A.
97.5
97.8
N.A.
80.6
95
93.7
92.8
N.A.
N.A.
77.6
73.2
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
N.A.
93.3
80
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
N.A.
93.3
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
46.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
85
0
0
0
0
0
93
% E
% Phe:
93
0
0
0
0
8
8
0
0
0
0
93
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
93
0
0
% G
% His:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
93
8
0
0
0
93
0
0
0
0
0
% K
% Leu:
0
93
0
0
0
0
0
0
0
0
0
0
0
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
47
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
85
0
0
0
0
0
0
93
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
77
85
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
85
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _