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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OGDH All Species: 27.88
Human Site: T33 Identified Species: 51.11
UniProt: Q02218 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02218 NP_001003941.1 1023 115935 T33 N R P A A A R T F Q Q I R C Y
Chimpanzee Pan troglodytes XP_001146956 1023 115904 T33 N R P A A A R T F Q Q I R C Y
Rhesus Macaque Macaca mulatta XP_001089063 1023 115873 T33 N R P A A A R T F Q Q I R C Y
Dog Lupus familis XP_532722 881 99572
Cat Felis silvestris
Mouse Mus musculus Q60597 1023 116430 T33 N K P A A I R T F Q Q I R C Y
Rat Rattus norvegicus Q5XI78 1023 116277 T33 N K P A A I R T F Q Q I R C Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509039 937 105661 S33 Q G G G G C G S R R A S S G A
Chicken Gallus gallus NP_001026553 1016 115163 T33 Q R P A A P R T F H P I R C Y
Frog Xenopus laevis Q6P6Z8 1021 115614 T33 N R P A A P R T F Q Q F R C L
Zebra Danio Brachydanio rerio NP_957073 1022 115620 T34 G P A A T P R T F Q P L R C F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391838 1029 116125 V42 T R T T Q V M V A K S A R K Y
Nematode Worm Caenorhab. elegans O61199 1029 115643 V35 H I S A S T L V Q H R N Q S V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20967 1014 114398 L36 V K I V G R G L A T T G T D N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.9 80.4 N.A. 95.8 96.2 N.A. 73 91.4 90.1 86.5 N.A. N.A. 65.1 56.1 N.A.
Protein Similarity: 100 99.9 99.9 82.4 N.A. 97.5 97.8 N.A. 80.6 95 93.7 92.8 N.A. N.A. 77.6 73.2 N.A.
P-Site Identity: 100 100 100 0 N.A. 86.6 86.6 N.A. 0 73.3 80 46.6 N.A. N.A. 20 6.6 N.A.
P-Site Similarity: 100 100 100 0 N.A. 93.3 93.3 N.A. 13.3 73.3 80 60 N.A. N.A. 26.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 46.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 63.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 70 54 24 0 0 16 0 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 62 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 62 0 0 8 0 0 8 % F
% Gly: 8 8 8 8 16 0 16 0 0 0 0 8 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 16 0 0 0 0 0 47 0 0 0 % I
% Lys: 0 24 0 0 0 0 0 0 0 8 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 0 8 8 0 0 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 47 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 8 54 0 0 24 0 0 0 0 16 0 0 0 0 % P
% Gln: 16 0 0 0 8 0 0 0 8 54 47 0 8 0 0 % Q
% Arg: 0 47 0 0 0 8 62 0 8 8 8 0 70 0 0 % R
% Ser: 0 0 8 0 8 0 0 8 0 0 8 8 8 8 0 % S
% Thr: 8 0 8 8 8 8 0 62 0 8 8 0 8 0 0 % T
% Val: 8 0 0 8 0 8 0 16 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _