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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX6A2 All Species: 4.55
Human Site: Y48 Identified Species: 11.11
UniProt: Q02221 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02221 NP_005196.1 97 10815 Y48 A L C T F N S Y L H S G H R P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112927 97 10840 Y48 A L C T F N S Y L H S G H R P
Dog Lupus familis XP_536907 97 10758 W48 A L C T L N S W L H A G H H E
Cat Felis silvestris
Mouse Mus musculus P43023 97 10731 W48 A L C S L N C W M H A G H H E
Rat Rattus norvegicus P10817 94 10468 M46 L C S L N C W M H A G H H E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510407 75 8765 E26 M L N A Y L K E Q Q H S G H E
Chicken Gallus gallus XP_415270 108 11797 L58 V C M L N C Y L K A Q H E H E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001004680 103 11252 K52 C M A N V Y L K M Q A H S H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20779 128 14724 H74 M Y A A F K D H K K H M S H E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32799 129 15003 A64 W V A L P A I A L T A V N T Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.7 81.4 N.A. 78.3 74.2 N.A. 46.3 56.4 N.A. 59.2 N.A. N.A. N.A. 29.6 N.A.
Protein Similarity: 100 N.A. 95.8 86.5 N.A. 86.5 83.5 N.A. 51.5 64.8 N.A. 70.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 N.A. 100 66.6 N.A. 46.6 6.6 N.A. 6.6 0 N.A. 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 100 80 N.A. 73.3 6.6 N.A. 13.3 0 N.A. 20 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 30 20 0 10 0 10 0 20 40 0 0 0 0 % A
% Cys: 10 20 40 0 0 20 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 10 10 60 % E
% Phe: 0 0 0 0 30 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 40 10 0 0 % G
% His: 0 0 0 0 0 0 0 10 10 40 20 30 50 60 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 10 10 20 10 0 0 0 0 0 % K
% Leu: 10 50 0 30 20 10 10 10 40 0 0 0 0 0 0 % L
% Met: 20 10 10 0 0 0 0 10 20 0 0 10 0 0 0 % M
% Asn: 0 0 10 10 20 40 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 20 % P
% Gln: 0 0 0 0 0 0 0 0 10 20 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 10 % R
% Ser: 0 0 10 10 0 0 30 0 0 0 20 10 20 0 0 % S
% Thr: 0 0 0 30 0 0 0 0 0 10 0 0 0 10 0 % T
% Val: 10 10 0 0 10 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 10 0 0 0 0 0 10 20 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 10 10 20 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _