Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPE All Species: 8.48
Human Site: S2642 Identified Species: 15.56
UniProt: Q02224 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02224 NP_001804.2 2701 316415 S2642 V P K E S P K S C F F D S R S
Chimpanzee Pan troglodytes XP_001170168 2701 316707 S2642 V P K E S P K S W F F D S R S
Rhesus Macaque Macaca mulatta XP_001110512 2701 316828 S2642 M P K E S P K S W F F D S R S
Dog Lupus familis XP_852631 1216 141588 V1158 I E M E R L E V A Q K L H E N
Cat Felis silvestris
Mouse Mus musculus Q6RT24 2474 286506 P2415 D P V P K D S P K S W F F D N
Rat Rattus norvegicus Q7TSP2 1385 159522 M1327 R T C Q E M E M L R K Q L E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420670 2150 248600 V2092 E S L S Q E T V T Q Y I S K P
Frog Xenopus laevis NP_001080954 2954 339950 N2868 G K T G L H K N L T E S T L F
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524993 2013 231091 H1955 K N R R I S V H D E R R Q S Y
Honey Bee Apis mellifera XP_001121311 1418 164919 N1360 A C Q T I P N N T V R F C G T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781622 2537 290578 K2458 Q G K Y D K L K S L A E Q K T
Poplar Tree Populus trichocarpa XP_002308893 1247 142380 A1189 M R L R G T Q A K S D A F H F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187629 1348 152938 E1290 A I N M G S K E D K A D N P A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.7 37.8 N.A. 60.5 21.2 N.A. N.A. 37.1 31 N.A. N.A. 26.1 24.8 N.A. 25.5
Protein Similarity: 100 99.2 98 42 N.A. 75 35.7 N.A. N.A. 55 52.2 N.A. N.A. 45.6 37.8 N.A. 48.8
P-Site Identity: 100 93.3 86.6 6.6 N.A. 6.6 0 N.A. N.A. 6.6 6.6 N.A. N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 93.3 93.3 26.6 N.A. 20 13.3 N.A. N.A. 20 20 N.A. N.A. 6.6 26.6 N.A. 26.6
Percent
Protein Identity: 23.9 N.A. N.A. 24.9 N.A. N.A.
Protein Similarity: 34.6 N.A. N.A. 37.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 0 0 0 8 8 0 16 8 0 0 8 % A
% Cys: 0 8 8 0 0 0 0 0 8 0 0 0 8 0 0 % C
% Asp: 8 0 0 0 8 8 0 0 16 0 8 31 0 8 0 % D
% Glu: 8 8 0 31 8 8 16 8 0 8 8 8 0 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 24 24 16 16 0 24 % F
% Gly: 8 8 0 8 16 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 0 8 8 0 % H
% Ile: 8 8 0 0 16 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 8 8 31 0 8 8 39 8 16 8 16 0 0 16 0 % K
% Leu: 0 0 16 0 8 8 8 0 16 8 0 8 8 8 0 % L
% Met: 16 0 8 8 0 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 8 16 0 0 0 0 8 0 16 % N
% Pro: 0 31 0 8 0 31 0 8 0 0 0 0 0 8 8 % P
% Gln: 8 0 8 8 8 0 8 0 0 16 0 8 16 0 0 % Q
% Arg: 8 8 8 16 8 0 0 0 0 8 16 8 0 24 0 % R
% Ser: 0 8 0 8 24 16 8 24 8 16 0 8 31 8 24 % S
% Thr: 0 8 8 8 0 8 8 0 16 8 0 0 8 0 16 % T
% Val: 16 0 8 0 0 0 8 16 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 16 0 8 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _