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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF23
All Species:
26.06
Human Site:
S125
Identified Species:
44.1
UniProt:
Q02241
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02241
NP_004847.2
960
110059
S125
K
T
H
T
M
T
G
S
P
G
E
G
G
L
L
Chimpanzee
Pan troglodytes
XP_001174899
959
109984
S125
K
T
H
T
M
T
G
S
P
G
E
G
G
L
L
Rhesus Macaque
Macaca mulatta
XP_001086180
956
109643
S125
K
T
H
T
M
T
G
S
P
G
E
G
G
L
L
Dog
Lupus familis
XP_535528
929
106546
R110
G
E
G
G
L
L
P
R
C
L
D
M
I
F
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_077207
953
108757
S125
K
T
Y
T
M
T
G
S
P
G
S
G
G
L
L
Rat
Rattus norvegicus
NP_001101625
952
108772
S125
K
T
Y
T
M
T
G
S
P
G
S
G
G
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508348
973
110874
S125
K
T
H
T
M
T
G
S
P
G
D
G
G
L
L
Chicken
Gallus gallus
Q5ZLK6
797
86563
L57
G
G
P
P
G
A
A
L
P
P
R
G
P
K
H
Frog
Xenopus laevis
NP_001088544
783
89786
E43
P
L
S
P
P
D
Q
E
C
C
I
E
V
I
N
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477025
887
100649
N139
K
T
Y
T
M
T
G
N
L
R
H
R
G
I
M
Honey Bee
Apis mellifera
XP_624886
843
96284
N103
V
A
L
P
L
V
E
N
V
I
R
G
R
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999659
870
99519
T122
K
T
Y
T
M
Q
G
T
P
T
D
G
G
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53086
805
91072
E65
D
I
D
I
D
A
E
E
G
S
T
R
S
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.7
91.7
N.A.
88.9
88.8
N.A.
83.6
21.9
61.7
26
N.A.
38.6
40.2
N.A.
45.3
Protein Similarity:
100
99.6
99.1
94.3
N.A.
94.7
95
N.A.
90.6
38.6
70
40
N.A.
58
58.3
N.A.
61.9
P-Site Identity:
100
100
100
0
N.A.
86.6
86.6
N.A.
93.3
13.3
0
0
N.A.
46.6
6.6
N.A.
60
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
100
13.3
6.6
0
N.A.
73.3
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
15
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
0
0
0
0
22
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
15
15
0
0
22
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
15
8
8
8
8
0
58
0
8
43
0
65
58
0
0
% G
% His:
0
0
29
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
8
0
8
0
0
0
0
0
8
8
0
8
15
0
% I
% Lys:
58
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% K
% Leu:
0
8
8
0
15
8
0
8
8
8
0
0
0
43
50
% L
% Met:
0
0
0
0
58
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
8
15
% N
% Pro:
8
0
8
22
8
0
8
0
58
8
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
15
15
8
0
8
% R
% Ser:
0
0
8
0
0
0
0
43
0
8
15
0
8
0
8
% S
% Thr:
0
58
0
58
0
50
0
8
0
8
8
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _