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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF23 All Species: 27.27
Human Site: S889 Identified Species: 46.15
UniProt: Q02241 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02241 NP_004847.2 960 110059 S889 K T R G G G Q S V Q F T D I E
Chimpanzee Pan troglodytes XP_001174899 959 109984 S889 K T R G G G Q S V Q F T D I E
Rhesus Macaque Macaca mulatta XP_001086180 956 109643 S889 K T R G G G Q S V Q F T D I E
Dog Lupus familis XP_535528 929 106546 S859 K T R G G G Q S V Q F T D I E
Cat Felis silvestris
Mouse Mus musculus NP_077207 953 108757 S882 K T R G G G Q S V Q F T D I E
Rat Rattus norvegicus NP_001101625 952 108772 S881 K T R G G G Q S V Q F T D I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508348 973 110874 S902 K T R G G G Q S V Q F T D V E
Chicken Gallus gallus Q5ZLK6 797 86563 K730 S I P V F S M K G S S I P K P
Frog Xenopus laevis NP_001088544 783 89786 I716 Q S V Q F T D I E T L R Q Q S
Zebra Danio Brachydanio rerio A8WFU8 634 70574 I567 L E Q S R K K I L Q T L N S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477025 887 100649 G820 N V I P T C G G G A Q V V F N
Honey Bee Apis mellifera XP_624886 843 96284 E776 H D T D G E L E T K L F K G D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999659 870 99519 A798 P T R G G G R A V Q F T D V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53086 805 91072 M738 P D L S P S P M I E P Q P E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.7 91.7 N.A. 88.9 88.8 N.A. 83.6 21.9 61.7 26 N.A. 38.6 40.2 N.A. 45.3
Protein Similarity: 100 99.6 99.1 94.3 N.A. 94.7 95 N.A. 90.6 38.6 70 40 N.A. 58 58.3 N.A. 61.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 0 0 6.6 N.A. 0 6.6 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 0 13.3 33.3 N.A. 0 20 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 8 0 0 8 0 0 0 0 0 58 0 8 % D
% Glu: 0 8 0 0 0 8 0 8 8 8 0 0 0 8 58 % E
% Phe: 0 0 0 0 15 0 0 0 0 0 58 8 0 8 0 % F
% Gly: 0 0 0 58 65 58 8 8 15 0 0 0 0 8 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 15 8 0 0 8 0 43 0 % I
% Lys: 50 0 0 0 0 8 8 8 0 8 0 0 8 8 0 % K
% Leu: 8 0 8 0 0 0 8 0 8 0 15 8 0 0 8 % L
% Met: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 15 0 8 8 8 0 8 0 0 0 8 0 15 0 8 % P
% Gln: 8 0 8 8 0 0 50 0 0 65 8 8 8 8 0 % Q
% Arg: 0 0 58 0 8 0 8 0 0 0 0 8 0 0 0 % R
% Ser: 8 8 0 15 0 15 0 50 0 8 8 0 0 8 8 % S
% Thr: 0 58 8 0 8 8 0 0 8 8 8 58 0 0 0 % T
% Val: 0 8 8 8 0 0 0 0 58 0 0 8 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _