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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH6A1
All Species:
10.61
Human Site:
S18
Identified Species:
17.95
UniProt:
Q02252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02252
NP_005580.1
535
57840
S18
R
A
R
I
L
Q
V
S
S
K
V
K
S
S
P
Chimpanzee
Pan troglodytes
XP_522903
535
57840
S18
R
A
R
I
L
Q
V
S
S
K
V
K
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001093055
537
57955
S20
R
A
R
I
L
Q
V
S
S
K
V
K
S
N
S
Dog
Lupus familis
XP_547901
533
57750
Q16
A
M
R
A
R
I
L
Q
V
S
S
K
V
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ20
535
57897
V18
M
R
S
R
I
L
Q
V
S
S
K
V
N
A
T
Rat
Rattus norvegicus
Q02253
535
57789
V18
V
R
S
R
I
L
Q
V
S
S
K
V
N
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421260
538
58274
L21
R
R
R
V
A
L
R
L
P
R
R
A
G
V
P
Frog
Xenopus laevis
NP_001089889
523
56695
A10
R
I
R
G
I
V
R
A
S
A
H
L
R
Q
A
Zebra Danio
Brachydanio rerio
NP_001002374
525
57101
S8
M
A
A
I
L
V
R
S
I
V
K
R
R
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KW39
520
55954
G8
M
S
L
V
R
L
I
G
A
E
A
R
H
L
A
Honey Bee
Apis mellifera
XP_393234
520
56023
K9
A
L
L
A
K
L
V
K
C
E
A
Y
F
A
A
Nematode Worm
Caenorhab. elegans
P52713
523
56443
V8
M
L
S
R
L
A
R
V
Q
P
K
C
Q
Q
L
Sea Urchin
Strong. purpuratus
XP_783603
565
61106
D49
I
L
K
W
A
M
Q
D
G
I
G
V
I
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WM29
607
65908
A92
P
L
R
P
Q
F
L
A
L
R
S
S
W
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
95.8
N.A.
94.7
95.3
N.A.
N.A.
83.6
79.8
80.5
N.A.
65
60.1
65
67
Protein Similarity:
100
99.8
98.5
98.5
N.A.
98.5
98.5
N.A.
N.A.
91.8
92.3
89.9
N.A.
82.2
80
80
79.8
P-Site Identity:
100
100
86.6
13.3
N.A.
6.6
13.3
N.A.
N.A.
20
20
33.3
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
100
93.3
26.6
N.A.
26.6
26.6
N.A.
N.A.
33.3
33.3
40
N.A.
40
20
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
29
8
15
15
8
0
15
8
8
15
8
0
15
22
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
8
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
8
8
0
29
22
8
8
0
8
8
0
0
8
0
0
% I
% Lys:
0
0
8
0
8
0
0
8
0
22
29
29
0
0
0
% K
% Leu:
0
29
15
0
36
36
15
8
8
0
0
8
0
15
8
% L
% Met:
29
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
15
15
0
% N
% Pro:
8
0
0
8
0
0
0
0
8
8
0
0
0
8
29
% P
% Gln:
0
0
0
0
8
22
22
8
8
0
0
0
8
15
0
% Q
% Arg:
36
22
50
22
15
0
29
0
0
15
8
15
15
0
0
% R
% Ser:
0
8
22
0
0
0
0
29
43
22
15
8
22
22
22
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% T
% Val:
8
0
0
15
0
15
29
22
8
8
22
22
8
15
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _