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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH6A1
All Species:
22.73
Human Site:
S228
Identified Species:
38.46
UniProt:
Q02252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02252
NP_005580.1
535
57840
S228
L
A
K
L
L
Q
D
S
G
A
P
D
G
T
L
Chimpanzee
Pan troglodytes
XP_522903
535
57840
S228
L
A
K
L
L
Q
D
S
G
A
P
D
G
T
L
Rhesus Macaque
Macaca mulatta
XP_001093055
537
57955
S230
L
A
K
L
L
Q
D
S
G
A
P
D
G
T
L
Dog
Lupus familis
XP_547901
533
57750
S226
L
A
K
L
L
Q
D
S
G
A
P
D
G
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ20
535
57897
S228
L
A
K
L
L
Q
D
S
G
A
P
D
G
T
L
Rat
Rattus norvegicus
Q02253
535
57789
S228
L
A
K
L
L
Q
D
S
G
A
P
D
G
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421260
538
58274
A231
L
A
K
L
F
Q
D
A
G
A
P
D
G
T
L
Frog
Xenopus laevis
NP_001089889
523
56695
A216
L
A
Q
L
M
Q
D
A
G
V
P
D
G
T
L
Zebra Danio
Brachydanio rerio
NP_001002374
525
57101
A218
L
A
K
L
L
Q
D
A
G
A
P
D
G
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KW39
520
55954
A214
L
M
E
L
L
N
E
A
G
C
P
P
G
V
V
Honey Bee
Apis mellifera
XP_393234
520
56023
A214
L
A
D
L
F
T
R
A
G
A
P
P
G
L
L
Nematode Worm
Caenorhab. elegans
P52713
523
56443
A218
L
V
E
L
A
K
E
A
G
V
P
D
G
C
V
Sea Urchin
Strong. purpuratus
XP_783603
565
61106
A259
L
A
E
L
A
Q
E
A
G
L
P
D
G
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WM29
607
65908
A302
L
A
E
L
A
M
E
A
G
L
P
D
G
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
95.8
N.A.
94.7
95.3
N.A.
N.A.
83.6
79.8
80.5
N.A.
65
60.1
65
67
Protein Similarity:
100
99.8
98.5
98.5
N.A.
98.5
98.5
N.A.
N.A.
91.8
92.3
89.9
N.A.
82.2
80
80
79.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
73.3
93.3
N.A.
40
53.3
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
66.6
60
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
86
0
0
22
0
0
58
0
65
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
65
0
0
0
0
86
0
0
0
% D
% Glu:
0
0
29
0
0
0
29
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
100
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
58
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
100
0
0
100
58
0
0
0
0
15
0
0
0
8
79
% L
% Met:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
15
0
0
0
% P
% Gln:
0
0
8
0
0
72
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
65
0
% T
% Val:
0
8
0
0
0
0
0
0
0
15
0
0
0
22
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _