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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH6A1
All Species:
8.48
Human Site:
S23
Identified Species:
14.36
UniProt:
Q02252
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02252
NP_005580.1
535
57840
S23
Q
V
S
S
K
V
K
S
S
P
T
W
Y
S
A
Chimpanzee
Pan troglodytes
XP_522903
535
57840
S23
Q
V
S
S
K
V
K
S
S
P
T
W
Y
S
A
Rhesus Macaque
Macaca mulatta
XP_001093055
537
57955
S25
Q
V
S
S
K
V
K
S
N
S
A
W
Y
S
A
Dog
Lupus familis
XP_547901
533
57750
V21
I
L
Q
V
S
S
K
V
N
S
T
W
Y
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ20
535
57897
N23
L
Q
V
S
S
K
V
N
A
T
W
Y
P
A
S
Rat
Rattus norvegicus
Q02253
535
57789
N23
L
Q
V
S
S
K
V
N
S
T
W
Y
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421260
538
58274
G26
L
R
L
P
R
R
A
G
V
P
W
I
A
S
A
Frog
Xenopus laevis
NP_001089889
523
56695
R15
V
R
A
S
A
H
L
R
Q
A
N
F
S
S
S
Zebra Danio
Brachydanio rerio
NP_001002374
525
57101
R13
V
R
S
I
V
K
R
R
V
P
L
Q
V
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KW39
520
55954
H13
L
I
G
A
E
A
R
H
L
A
K
R
S
Y
S
Honey Bee
Apis mellifera
XP_393234
520
56023
F14
L
V
K
C
E
A
Y
F
A
A
R
T
Y
S
S
Nematode Worm
Caenorhab. elegans
P52713
523
56443
Q13
A
R
V
Q
P
K
C
Q
Q
L
A
H
F
S
T
Sea Urchin
Strong. purpuratus
XP_783603
565
61106
I54
M
Q
D
G
I
G
V
I
P
M
S
T
K
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WM29
607
65908
W97
F
L
A
L
R
S
S
W
L
S
T
S
P
E
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
95.8
N.A.
94.7
95.3
N.A.
N.A.
83.6
79.8
80.5
N.A.
65
60.1
65
67
Protein Similarity:
100
99.8
98.5
98.5
N.A.
98.5
98.5
N.A.
N.A.
91.8
92.3
89.9
N.A.
82.2
80
80
79.8
P-Site Identity:
100
100
80
33.3
N.A.
6.6
13.3
N.A.
N.A.
20
13.3
13.3
N.A.
0
20
6.6
0
P-Site Similarity:
100
100
86.6
46.6
N.A.
40
40
N.A.
N.A.
26.6
33.3
20
N.A.
33.3
40
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
8
8
15
8
0
15
22
15
0
8
15
36
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
15
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% F
% Gly:
0
0
8
8
0
8
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
8
0
8
8
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
22
29
29
0
0
0
8
0
8
0
0
% K
% Leu:
36
15
8
8
0
0
8
0
15
8
8
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
15
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
0
0
8
29
0
0
22
15
0
% P
% Gln:
22
22
8
8
0
0
0
8
15
0
0
8
0
0
8
% Q
% Arg:
0
29
0
0
15
8
15
15
0
0
8
8
0
0
8
% R
% Ser:
0
0
29
43
22
15
8
22
22
22
8
8
15
50
36
% S
% Thr:
0
0
0
0
0
0
0
0
0
15
29
15
0
0
8
% T
% Val:
15
29
22
8
8
22
22
8
15
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
22
29
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
15
36
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _