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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH6A1
All Species:
56.36
Human Site:
S258
Identified Species:
95.38
UniProt:
Q02252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02252
NP_005580.1
535
57840
S258
H
P
D
I
K
A
I
S
F
V
G
S
N
K
A
Chimpanzee
Pan troglodytes
XP_522903
535
57840
S258
H
P
D
I
K
A
I
S
F
V
G
S
N
K
A
Rhesus Macaque
Macaca mulatta
XP_001093055
537
57955
S260
H
P
D
I
K
A
I
S
F
V
G
S
N
Q
A
Dog
Lupus familis
XP_547901
533
57750
S256
H
P
D
I
K
A
I
S
F
V
G
S
N
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ20
535
57897
S258
H
P
D
I
K
A
I
S
F
V
G
S
N
Q
A
Rat
Rattus norvegicus
Q02253
535
57789
S258
H
P
D
I
K
A
I
S
F
V
G
S
N
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421260
538
58274
S261
H
P
D
I
R
A
I
S
F
V
G
S
N
Q
A
Frog
Xenopus laevis
NP_001089889
523
56695
S246
H
P
A
I
R
A
I
S
F
V
G
S
N
Q
A
Zebra Danio
Brachydanio rerio
NP_001002374
525
57101
S248
H
P
A
I
R
A
I
S
F
V
G
S
N
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KW39
520
55954
S244
A
P
E
I
K
A
V
S
F
V
G
S
D
Q
A
Honey Bee
Apis mellifera
XP_393234
520
56023
S244
H
P
D
I
K
A
V
S
F
V
G
S
D
Q
A
Nematode Worm
Caenorhab. elegans
P52713
523
56443
S248
N
P
D
I
K
A
I
S
F
V
G
G
D
A
A
Sea Urchin
Strong. purpuratus
XP_783603
565
61106
S289
H
P
Y
I
R
A
V
S
F
V
G
S
D
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WM29
607
65908
S332
D
E
D
I
R
A
V
S
F
V
G
S
N
T
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
95.8
N.A.
94.7
95.3
N.A.
N.A.
83.6
79.8
80.5
N.A.
65
60.1
65
67
Protein Similarity:
100
99.8
98.5
98.5
N.A.
98.5
98.5
N.A.
N.A.
91.8
92.3
89.9
N.A.
82.2
80
80
79.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
80
N.A.
66.6
80
73.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
93.3
100
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
100
0
0
0
0
0
0
0
8
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
72
0
0
0
0
0
0
0
0
0
29
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
100
8
0
0
0
% G
% His:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
72
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
65
0
0
0
0
0
0
0
0
15
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% N
% Pro:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% Q
% Arg:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
93
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
29
0
0
100
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _