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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH6A1
All Species:
41.82
Human Site:
S53
Identified Species:
70.77
UniProt:
Q02252
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02252
NP_005580.1
535
57840
S53
G
K
F
V
E
S
K
S
D
K
W
I
D
I
H
Chimpanzee
Pan troglodytes
XP_522903
535
57840
S53
G
K
F
V
E
S
K
S
D
K
W
I
D
I
H
Rhesus Macaque
Macaca mulatta
XP_001093055
537
57955
S55
G
K
F
V
E
S
K
S
D
K
W
I
E
I
H
Dog
Lupus familis
XP_547901
533
57750
S51
G
K
F
V
E
S
K
S
D
K
W
I
D
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ20
535
57897
S53
G
K
F
V
E
S
K
S
D
K
W
I
D
I
H
Rat
Rattus norvegicus
Q02253
535
57789
S53
G
K
F
V
E
S
K
S
D
K
W
I
D
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421260
538
58274
T56
G
K
F
V
E
S
K
T
T
E
W
I
D
I
H
Frog
Xenopus laevis
NP_001089889
523
56695
I45
D
S
E
T
S
E
W
I
D
V
H
N
P
A
T
Zebra Danio
Brachydanio rerio
NP_001002374
525
57101
S43
G
K
F
V
E
S
K
S
S
Q
W
L
D
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KW39
520
55954
I43
E
S
K
T
N
E
W
I
D
V
H
D
P
A
T
Honey Bee
Apis mellifera
XP_393234
520
56023
D44
S
K
A
T
E
F
T
D
V
H
D
P
A
T
N
Nematode Worm
Caenorhab. elegans
P52713
523
56443
T43
G
Q
A
V
E
S
K
T
T
D
F
V
E
L
T
Sea Urchin
Strong. purpuratus
XP_783603
565
61106
T84
G
K
M
V
E
S
Q
T
T
E
W
I
D
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WM29
607
65908
S127
G
S
F
V
E
S
Q
S
S
S
F
I
D
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
95.8
N.A.
94.7
95.3
N.A.
N.A.
83.6
79.8
80.5
N.A.
65
60.1
65
67
Protein Similarity:
100
99.8
98.5
98.5
N.A.
98.5
98.5
N.A.
N.A.
91.8
92.3
89.9
N.A.
82.2
80
80
79.8
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
80
6.6
80
N.A.
6.6
13.3
33.3
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
6.6
93.3
N.A.
6.6
20
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
0
0
0
0
0
0
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
58
8
8
8
65
0
0
% D
% Glu:
8
0
8
0
86
15
0
0
0
15
0
0
15
0
0
% E
% Phe:
0
0
65
0
0
8
0
0
0
0
15
0
0
0
0
% F
% Gly:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
15
0
0
0
65
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
0
65
0
58
8
% I
% Lys:
0
72
8
0
0
0
65
0
0
43
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
15
0
0
% P
% Gln:
0
8
0
0
0
0
15
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
22
0
0
8
79
0
58
15
8
0
0
0
0
0
% S
% Thr:
0
0
0
22
0
0
8
22
22
0
0
0
0
8
22
% T
% Val:
0
0
0
79
0
0
0
0
8
15
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
65
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _