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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH6A1 All Species: 8.48
Human Site: T26 Identified Species: 14.36
UniProt: Q02252 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02252 NP_005580.1 535 57840 T26 S K V K S S P T W Y S A S S F
Chimpanzee Pan troglodytes XP_522903 535 57840 T26 S K V K S S P T W Y S A S S F
Rhesus Macaque Macaca mulatta XP_001093055 537 57955 A28 S K V K S N S A W Y S A S S F
Dog Lupus familis XP_547901 533 57750 T24 V S S K V N S T W Y P A Y S F
Cat Felis silvestris
Mouse Mus musculus Q9EQ20 535 57897 W26 S S K V N A T W Y P A S S F S
Rat Rattus norvegicus Q02253 535 57789 W26 S S K V N S T W Y P A S S F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421260 538 58274 W29 P R R A G V P W I A S A A A S
Frog Xenopus laevis NP_001089889 523 56695 N18 S A H L R Q A N F S S S A A V
Zebra Danio Brachydanio rerio NP_001002374 525 57101 L16 I V K R R V P L Q V G R M C Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KW39 520 55954 K16 A E A R H L A K R S Y S S A A
Honey Bee Apis mellifera XP_393234 520 56023 R17 C E A Y F A A R T Y S S S I P
Nematode Worm Caenorhab. elegans P52713 523 56443 A16 Q P K C Q Q L A H F S T S K S
Sea Urchin Strong. purpuratus XP_783603 565 61106 S57 G I G V I P M S T K P D H I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WM29 607 65908 T100 L R S S W L S T S P E Q S T Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 95.8 N.A. 94.7 95.3 N.A. N.A. 83.6 79.8 80.5 N.A. 65 60.1 65 67
Protein Similarity: 100 99.8 98.5 98.5 N.A. 98.5 98.5 N.A. N.A. 91.8 92.3 89.9 N.A. 82.2 80 80 79.8
P-Site Identity: 100 100 80 46.6 N.A. 13.3 20 N.A. N.A. 20 13.3 6.6 N.A. 6.6 20 13.3 0
P-Site Similarity: 100 100 86.6 53.3 N.A. 46.6 46.6 N.A. N.A. 40 40 20 N.A. 40 40 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. 51.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 68.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 8 0 15 22 15 0 8 15 36 15 22 8 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 15 0 0 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 8 8 0 0 0 15 29 % F
% Gly: 8 0 8 0 8 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 8 0 8 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 8 8 0 0 8 0 0 0 8 0 0 0 0 15 8 % I
% Lys: 0 22 29 29 0 0 0 8 0 8 0 0 0 8 0 % K
% Leu: 8 0 0 8 0 15 8 8 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 15 15 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 0 8 29 0 0 22 15 0 0 0 8 % P
% Gln: 8 0 0 0 8 15 0 0 8 0 0 8 0 0 8 % Q
% Arg: 0 15 8 15 15 0 0 8 8 0 0 8 0 0 0 % R
% Ser: 43 22 15 8 22 22 22 8 8 15 50 36 65 29 29 % S
% Thr: 0 0 0 0 0 0 15 29 15 0 0 8 0 8 0 % T
% Val: 8 8 22 22 8 15 0 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 22 29 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 15 36 8 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _