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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH6A1
All Species:
35.76
Human Site:
T495
Identified Species:
60.51
UniProt:
Q02252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02252
NP_005580.1
535
57840
T495
R
S
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Chimpanzee
Pan troglodytes
XP_522903
535
57840
T495
R
S
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Rhesus Macaque
Macaca mulatta
XP_001093055
537
57955
T497
R
S
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Dog
Lupus familis
XP_547901
533
57750
T493
R
S
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ20
535
57897
T495
R
S
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Rat
Rattus norvegicus
Q02253
535
57789
T495
R
S
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421260
538
58274
A498
R
A
S
F
R
G
D
A
N
F
Y
G
K
Q
G
Frog
Xenopus laevis
NP_001089889
523
56695
T483
R
A
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Zebra Danio
Brachydanio rerio
NP_001002374
525
57101
T485
R
G
S
F
R
G
D
T
N
F
Y
G
K
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KW39
520
55954
H481
R
G
S
F
R
G
D
H
H
F
Y
G
K
Q
G
Honey Bee
Apis mellifera
XP_393234
520
56023
N481
K
G
S
F
L
G
D
N
H
F
Y
G
K
H
G
Nematode Worm
Caenorhab. elegans
P52713
523
56443
G483
G
S
R
G
S
F
L
G
D
L
N
F
Y
G
K
Sea Urchin
Strong. purpuratus
XP_783603
565
61106
T526
R
G
S
F
K
G
D
T
N
F
Y
G
K
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WM29
607
65908
G567
G
N
K
A
S
F
A
G
D
L
N
F
Y
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
95.8
N.A.
94.7
95.3
N.A.
N.A.
83.6
79.8
80.5
N.A.
65
60.1
65
67
Protein Similarity:
100
99.8
98.5
98.5
N.A.
98.5
98.5
N.A.
N.A.
91.8
92.3
89.9
N.A.
82.2
80
80
79.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
93.3
N.A.
80
60
6.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
86.6
73.3
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
86
0
15
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
86
0
15
0
0
0
86
0
15
0
0
0
% F
% Gly:
15
29
0
8
0
86
0
15
0
0
0
86
0
15
86
% G
% His:
0
0
0
0
0
0
0
8
15
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
8
0
0
0
0
0
0
0
86
0
15
% K
% Leu:
0
0
0
0
8
0
8
0
0
15
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
72
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
79
0
% Q
% Arg:
79
0
8
0
72
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
86
0
15
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
86
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _