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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH6A1 All Species: 43.03
Human Site: T64 Identified Species: 72.82
UniProt: Q02252 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02252 NP_005580.1 535 57840 T64 I D I H N P A T N E V I G R V
Chimpanzee Pan troglodytes XP_522903 535 57840 T64 I D I H N P A T N E V I G R V
Rhesus Macaque Macaca mulatta XP_001093055 537 57955 T66 I E I H N P A T N E V I G R V
Dog Lupus familis XP_547901 533 57750 T62 I D I H N P A T N E V I G R V
Cat Felis silvestris
Mouse Mus musculus Q9EQ20 535 57897 T64 I D I H N P A T N E V V G R V
Rat Rattus norvegicus Q02253 535 57789 T64 I D I H N P A T N E V V G R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421260 538 58274 T67 I D I H N P A T N E V V A R V
Frog Xenopus laevis NP_001089889 523 56695 I56 N P A T N E V I G R V P Q A T
Zebra Danio Brachydanio rerio NP_001002374 525 57101 T54 L D I H N P A T S E V I G R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KW39 520 55954 V54 D P A T N Q V V T R V P K A T
Honey Bee Apis mellifera XP_393234 520 56023 C55 P A T N E L L C R T P K C T R
Nematode Worm Caenorhab. elegans P52713 523 56443 T54 V E L T N P A T N E V I A M V
Sea Urchin Strong. purpuratus XP_783603 565 61106 T95 I D V H N P A T N E V V T R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WM29 607 65908 T138 I D V I N P A T Q E V V S K V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 95.8 N.A. 94.7 95.3 N.A. N.A. 83.6 79.8 80.5 N.A. 65 60.1 65 67
Protein Similarity: 100 99.8 98.5 98.5 N.A. 98.5 98.5 N.A. N.A. 91.8 92.3 89.9 N.A. 82.2 80 80 79.8
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. N.A. 86.6 13.3 86.6 N.A. 13.3 0 60 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 13.3 100 N.A. 13.3 6.6 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. 51.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 68.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 60 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 0 0 0 79 0 0 0 0 0 15 15 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % C
% Asp: 8 65 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 15 0 0 8 8 0 0 0 79 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 50 0 0 % G
% His: 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 65 0 58 8 0 0 0 8 0 0 0 43 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 8 8 8 0 % K
% Leu: 8 0 8 0 0 8 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 0 0 8 93 0 0 0 65 0 0 0 0 0 0 % N
% Pro: 8 15 0 0 0 79 0 0 0 0 8 15 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 15 0 0 0 65 8 % R
% Ser: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % S
% Thr: 0 0 8 22 0 0 0 79 8 8 0 0 8 8 15 % T
% Val: 8 0 15 0 0 0 15 8 0 0 93 36 0 0 79 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _