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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH6A1 All Species: 42.73
Human Site: T96 Identified Species: 72.31
UniProt: Q02252 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02252 NP_005580.1 535 57840 T96 A F P A W A D T S V L S R Q Q
Chimpanzee Pan troglodytes XP_522903 535 57840 T96 A F P A W A D T S V L S R Q Q
Rhesus Macaque Macaca mulatta XP_001093055 537 57955 T98 A F P A W A D T S V L S R Q Q
Dog Lupus familis XP_547901 533 57750 T94 A F P A W A D T S V L S R Q Q
Cat Felis silvestris
Mouse Mus musculus Q9EQ20 535 57897 T96 A F P A W A D T S I L S R Q Q
Rat Rattus norvegicus Q02253 535 57789 T96 A F P A W A D T S I L S R Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421260 538 58274 T99 A F W N W S E T S V L S R Q Q
Frog Xenopus laevis NP_001089889 523 56695 S88 W S E T S I L S R Q Q I F L R
Zebra Danio Brachydanio rerio NP_001002374 525 57101 T86 A F Q T W S E T S I L A R Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KW39 520 55954 T86 W S N Q S I L T R Q Q V M F K
Honey Bee Apis mellifera XP_393234 520 56023 R87 K N T S V L T R Q T L M L K Y
Nematode Worm Caenorhab. elegans P52713 523 56443 T86 A F N T W K N T S P L T R Q Q
Sea Urchin Strong. purpuratus XP_783603 565 61106 T127 A F P A W S K T S V L T R Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WM29 607 65908 T170 A F P L W R N T P I T T R Q R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 95.8 N.A. 94.7 95.3 N.A. N.A. 83.6 79.8 80.5 N.A. 65 60.1 65 67
Protein Similarity: 100 99.8 98.5 98.5 N.A. 98.5 98.5 N.A. N.A. 91.8 92.3 89.9 N.A. 82.2 80 80 79.8
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 73.3 0 60 N.A. 6.6 6.6 60 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 13.3 86.6 N.A. 13.3 20 73.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 51.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 68.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 79 0 0 50 0 43 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 79 0 0 0 0 0 0 0 0 0 0 8 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 15 0 0 0 29 0 8 0 0 0 % I
% Lys: 8 0 0 0 0 8 8 0 0 0 0 0 0 8 8 % K
% Leu: 0 0 0 8 0 8 15 0 0 0 79 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 0 8 15 8 0 0 15 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 58 0 0 0 0 0 8 8 0 0 0 0 0 % P
% Gln: 0 0 8 8 0 0 0 0 8 15 15 0 0 79 72 % Q
% Arg: 0 0 0 0 0 8 0 8 15 0 0 0 79 0 15 % R
% Ser: 0 15 0 8 15 22 0 8 72 0 0 50 0 0 0 % S
% Thr: 0 0 8 22 0 0 8 86 0 8 8 22 0 0 0 % T
% Val: 0 0 0 0 8 0 0 0 0 43 0 8 0 0 0 % V
% Trp: 15 0 8 0 79 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _