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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP27A1
All Species:
11.52
Human Site:
S56
Identified Species:
28.15
UniProt:
Q02318
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02318
NP_000775.1
531
60235
S56
G
V
R
R
R
Q
R
S
L
E
E
I
P
R
L
Chimpanzee
Pan troglodytes
XP_001159436
531
60263
S56
G
V
R
R
R
Q
R
S
L
E
E
I
P
R
L
Rhesus Macaque
Macaca mulatta
XP_001095424
531
60385
S56
G
I
R
R
R
Q
R
S
L
K
E
I
P
R
L
Dog
Lupus familis
XP_853094
528
59479
E55
R
R
L
R
T
L
E
E
L
P
G
P
G
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG1
533
60702
P59
D
R
P
R
L
R
S
P
A
E
L
P
G
T
G
Rat
Rattus norvegicus
P17178
533
60715
L59
D
R
P
R
L
R
S
L
A
E
L
P
G
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422056
610
68642
D108
E
R
A
C
I
F
S
D
P
S
E
D
T
R
L
Frog
Xenopus laevis
NP_001087098
542
61748
E70
D
G
R
K
E
M
K
E
F
D
D
L
P
G
P
Zebra Danio
Brachydanio rerio
XP_001334004
522
60019
T50
D
G
H
R
K
L
K
T
E
A
D
L
P
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5L3
589
65883
K47
G
V
A
T
E
I
E
K
S
I
A
M
Q
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.6
N.A.
72
72.9
N.A.
N.A.
46
47
45.7
N.A.
26.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.3
86.6
N.A.
82.1
84.4
N.A.
N.A.
59.6
68
63.8
N.A.
42.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
20
N.A.
13.3
13.3
N.A.
N.A.
20
13.3
13.3
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
20
20
N.A.
N.A.
20
46.6
53.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
0
20
10
10
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
0
0
0
0
0
0
10
0
10
20
10
0
0
0
% D
% Glu:
10
0
0
0
20
0
20
20
10
40
40
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% F
% Gly:
40
20
0
0
0
0
0
0
0
0
10
0
30
10
20
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
10
0
0
0
10
0
30
0
0
10
% I
% Lys:
0
0
0
10
10
0
20
10
0
10
0
0
0
0
0
% K
% Leu:
0
0
10
0
20
20
0
10
40
0
20
20
0
0
60
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
20
0
0
0
0
10
10
10
0
30
50
10
10
% P
% Gln:
0
0
0
0
0
30
0
0
0
0
0
0
10
10
0
% Q
% Arg:
10
40
40
70
30
20
30
0
0
0
0
0
0
50
0
% R
% Ser:
0
0
0
0
0
0
30
30
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
10
10
0
0
10
0
0
0
0
10
10
0
% T
% Val:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _